Synephrine Powder

Premium Synephrine Powder 98% – Natural Weight Management Ingredient from ISO-Certified Manufacturer

Xi'an Jiayuan Bio-tech Co., Ltd. delivers pharmaceutical-grade Synephrine Powder extracted from Citrus aurantium fruit, standardized to 98% purity (CAS NO. 5985-28-4). Established in 2002 with a registered capital of RMB 30 million, we have two GMP certified manufacturing lines in Xi'an Hi-Tech Industrial Development Zone. This natural alkaloid is supplied to dietary supplement formulators, pharmaceutical makers and functional food producers in over 50 countries. 30 technical professionals ensure batch to batch variability within ± 2%. Our product is ISO9001, SGS and HALAL certified and provides a clean-label alternative to synthetic stimulants.

 

What Is Synephrine Powder?

The product is a bioactive alkaloid and is obtained from the dried unripe fruits of Citrus aurantium L. (bitter orange). White crystalline powder, chemical formula C9H13NO2·HCl, molecular weight 203.67, serves as an adrenergic receptor agonist.

It stimulates thermogenesis and lipolysis without overstimulating the central nervous system, unlike ephedrine. The chemical is included in the Nordic and German Pharmacopeias as a reference standard for the treatment of hypotension and bronchial asthma. Our extraction procedure preserves the native β-phenethylamine structure, and is of pharmaceutical-grade purity as verified by RP-HPLC at 275nm wavelength.

Specifications of Synephrine Powder

Attribute	Details
Product Name	Synephrine Powder
Botanical Source	Citrus aurantium
Purity	≥98%
Appearance	White to off-white powder
Solubility	Soluble in water
Shelf Life	Two years
Packaging	Customizable

Functions

This natural alkaloid has a number of physiological effects that have been clinically demonstrated:

Metabolic Enhancement: It activates β-3 adrenergic receptors in adipocytes, enhancing lipolysis rates without altering heart rate or blood pressure in controlled experiments. Animal tests demonstrate considerable decreases in Lee’s index and visceral fat deposition.

Gastrointestinal Regulation: The chemical regulates stomach smooth muscle via acetylcholine and 5-HT receptor pathways to ensure healthy digestive motility.

Cardiovascular Support: Mild vasoconstrictive qualities, effective in managing clinical hypotension. It also has bronchodilatory actions that are conducive to respiratory function.

Thermogenic Activity: Enhances calorie expenditure by stimulating mitochondrial activity in brown adipose tissue; beneficial in weight control formulations.

Application Fields

Industry Sector	Specific Applications	Typical Dosage Range
Dietary Supplements	Thermogenic capsules, sports nutrition pre-workouts, weight management tablets	10-50mg per serving
Pharmaceuticals	OTC hypotension remedies, bronchodilator syrups, reference standards for HPLC analysis	Per pharmacopeial guidelines
Functional Foods	Performance beverages, metabolic support drink mixes, wellness bars	5-20mg per serving
Research & Development	Analytical standards (10mg-100mg vials), bioavailability studies, formulation testing	Customized quantities

Our powder is easily incorporated into hard shell capsules, enteric coated tablets and water dispersible sachets. Formulators like its stability in high-speed encapsulation and compatibility with other plant extracts.

Certificates

• ISO9001 Quality Management System (certified 2012)
• SGS Product Verification
• HALAL Certification for global markets
• Shaanxi High-Tech Enterprise Recognition (2013)
• Independent Import/Export License

Our facility undergoes annual audits to maintain compliance with international food safety and pharmaceutical standards for Synephrine Powder.

Quality Control

Every manufacturing batch is tested in a rigorous multistage test:

Purity Analysis: RP-HPLC technique (50:50 methanol/potassium dihydrogen phosphate as mobile phase) reveals ≥98% content, detection at 275nm. Batch to batch variance is approximately ±2%.

Safety Testing:Heavy metals confirmed at Pb ≤1ppm, As ≤1ppm. Microbiological limits are USP compliant. Residual solvents (GC verified).

Physical Properties: Loss on drying <0.5%, D50 particle size 80-120 mesh for ideal flowability. Appearance: Confirmed as white to off-white powder.

Each shipment is accompanied by a Certificate of Analysis showing purity, moisture, microbiological counts and pesticide residues. Third party test results available upon request.

Payment & Shipment

Payment Methods: T/T (bank transfer), L/C at sight, Western Union, MoneyGram, Alibaba Trade Assurance

Lead Times:

• Sample orders (10-100g): 1-3 working days
• Commercial batches (1-500kg): 3-7 working days
• Bulk orders (500kg+): 7-14 days production + shipping

Logistics Partners: We cooperate with Fedex, DHL, TNT, EMS, UPS for express shipping (5-8 days door to door). Mid-size orders may be sent via air freight. Sea freight bulk cargoes from Shanghai/Tianjin/Qingdao ports is cost efficient (15-30 days).

Without any import expertise, we can also provide you customs clearance in Europe and North America to make sure your product arrives at your location without a hitch.

Packaging & Transportation

Standard Packaging:

• 1kg: Double-sealed aluminum foil bag with desiccant
• 25kg: Fiber drum with dual food-grade PE inner bags
• Analytical standards: 10mg/20mg/50mg/100mg amber glass vials

Storage Requirements: Store cool (<25°C), dry, prevent from light. Moisture absorption is prevented with sealed containers. The shelf life is 24 months under optimum circumstances.

Shipping Marks: Labels may be customized to include batch number, production date and storage instructions. All packages are IATA hazardous goods compliant for safe air shipment.

After-sales Service

You receive comprehensive technical support throughout the product lifecycle:

• Pre-sale formulation consultation for optimal ingredient integration
• Free samples (10-50g) for compatibility testing
• Regulatory documentation assistance (COA, allergen statements, non-GMO declarations)
• Complaint resolution within 24 hours with re-testing or replacement if quality issues arise
• Quarterly market insights on synephrine applications and regulatory updates

Our technical team provides guidance on optimal dosage, stability testing protocols, and label claim substantiation.

Exhibitions

We maintain active presence at international trade shows to connect with formulators and distributors:

• Vitafoods Europe (Geneva): Annual participation showcasing latest extraction technologies
• SupplySide West (Las Vegas): Networking hub for North American supplement buyers
• Fi Asia (Bangkok): Platform for ASEAN market engagement
• CPHI Worldwide: Pharmaceutical-grade ingredient exhibitions

Visit our booth to discuss custom specifications, bulk pricing, and supply agreements. Our sales team demonstrates analytical methods and shares application case studies.

Why Choose Us?

Direct Manufacturer Advantage We cut the middle man and pass those savings on to you. Flexible MOQs enable you to consolidate many ingredients in one shipment, helping you save logistical expenses.

Reliable Raw Material Supply: 22 years of experience and established farming agreements in the citrus belt of China assure the availability of raw materials throughout the year. 5+ tons in stock, quick shipment available.

Technical Depth 30 R&D personnel offer formulation assistance, stability testing and regulatory compliance help. We provide bioavailability improvement tactics and bespoke specifications (6%-98% purity range).

Experience in Global Logistics: We ship with door to door service to 50+ countries. International procurement is easy for you with EU and US markets customs clearance support.

FAQ

Q：How is quality consistency ensured across batches?

A：Each batch comes with a verifiable COA. Our specifications maintain 98% synephrine by HPLC with batch variability within ±2%. We test heavy metals (Pb ≤1-2ppm, As ≤1ppm), microbial limits per USP standards, and residual solvents. Shelf life is 24 months under proper storage.

Q：What is the lead time?

A：Sample/small orders ship within 1-3 working days. Commercial orders typically require 3-7 working days. Mass orders by sea take 15-30 days shipping time after production completion.

Q：What are the shipping options and packaging?

A：Courier services (DHL, FedEx, TNT, EMS) Delivery to door. Air freight 5-8 days Sea freight 15-30 days. Packaging: 1kg aluminum foil bags or 25kg fiber drums with double PE bags inside. Ports of Shipment Shanghai, Tianjin and Qingdao.

Q: What are the payment terms?

A：The most prevalent is T/T Bank transfer. We also accept L/C at sight, Western Union, MoneyGram and Alibaba Secure Payment for your convenience.

Q: Can you give regulatory help for diverse markets?

A: Yes. We provide paperwork for FDA GRAS filings, EU Novel Food evaluations and Health Canada NPN applications. Our staff can help develop ingredient declarations and allergy statements specific to your target market.

Contact Us

Ready to source reliable Synephrine Powder for your next formulation? Contact our technical sales team at sales@jayuanbio.com and sales1@jayuanbio.com  for COA samples, bulk pricing, and regulatory documentation.