Phellodendron Extract

Phellodendron Extract - Premium Berberine Botanical Solution for Global Health and Wellness Applications

Xi'an Jiayuan Bio-tech specializes in producing high-purity Phellodendron Extract standardized to Berberine Hydrochloride 97%, sourced from premium Phellodendron chinense roots. We have been producing since 2002 and have over 20 years of experience, two GMP compliant production lines and 30 technical professionals to guaranty constant quality. Our light yellow crystalline powder (CAS NO. 633-65-8, MW: 372.822) is approved by ISO9001, HALAL, KOSHER, and HACCP. It can be used as a reliable source of natural antibacterial solutions for the pharmaceutical, nutraceutical, and cosmetic industries around the world.

What Is Phellodendron Extract?

This product is a dried, typical product of plant prepared from roots or bark of Phellodendron amurense and Phellodendron chinense. The major active element is Berberine, an isoquinoline alkaloid. It is renowned for its broad spectrum of anti-bacterial and anti-inflammatory actions.

The extract we provide is a sustainable and cost effective alternative to synthetic antimicrobials. Phellodendron offers scalable manufacturing without loss of effectiveness unlike endangered botanical sources.

The extract is obtained as a fine light yellow crystalline powder with typical bitter flavor. High purity grades (≥ 97% Berberine HCl) exhibit exceptional thermal stability and are appropriate for a range of formulation applications including tablets, capsules and topical treatments.

COA of Phellodendron Extract

Product Name		Phellodendron Extract
Ref standard		Enterprise standard
Items		Requirements			Results
Character		This product is yellow crystalline powder, odorless, bitter taste			Conforms
Identification		Positive response			Conforms
Detection method		Titration			Conforms
Assay		≥90%			90.43%
Loss on drying		≤12%			11.25%
Residue on ignition		≤0.2%			0.15%
Heavy metal		≤10.0ppm			Conforms
Lead(Pb)		≤3.0ppm			0.05ppm
Arsenic (As)		≤2.0ppm			0.005ppm
Cadmium(Cd)		≤1.0ppm			0.060ppm
Mercury(Hg)		≤0. 10ppm			0.005ppm
Total Plate Count		≤1000cfu/g			Conforms
Mold counting		≤100 cfu/g			Conforms
E. Coli & Living mite		Not detectable			Non-detected
Conclusion		The product conforms to the enterprise standard

Core Functions

Antibacterial Activity: 100 % inactivation of Streptococcus mutans at 5mg/mL with no cytotoxicity. Excellent efficacy against Staphylococcus aureus, Escherichia coli and antibiotic resistant bacteria

Anti-inflammatory Effect: Greatly reduces the production of pro-inflammatory cytokines, including TNF-α and IL-1β. Inhibits the inflammatory pathways NF-κB and MAPK in the cell.

Metabolic health benefits: Stimulates AMPK pathways for blood sugar control. It possesses hypoglycaemic and anti-ulcer actions due to polysaccharide constituents.

Liver Protection Effect: Phellodendron polysaccharides possess antioxidant activity and enhance liver function via many routes.

Application Fields

Industry	Applications
Pharmaceuticals	Antibacterial formulations, gastrointestinal disorder treatments, diabetes adjunctive therapy
Cosmetics	Acne treatment products, anti-inflammatory creams, anti-aging serums, sun protection formulas
Dietary Supplements	Immune support capsules, metabolic health tablets, anti-inflammatory wellness products
Animal Nutrition	Residue-free intestinal infection treatments, feed additives for growth promotion

Certificates

• ISO9001 Quality Management System
• FSSC22000 Food Safety System Certification
• HALAL Certification
• KOSHER Certification
• HACCP System Certification

All certifications for Phellodendron Extract ensure compliance with international regulatory requirements across pharmaceutical, food, and cosmetic applications.

Quality Control

We use multi-stage quality assurance procedures:

HPLC Testing: Quantitative measurement of each batch to ensure the concentration of Berberine HCl is ≥97% according to the specification.

Identity Verification: HPTLC authenticates the real origin of Phellodendron chinense to avoid adultera tion with synthetic analogs or other non-target species.

Contaminant Screening: Confirmed by ICP-MS testing for heavy metals (Lead <3.0mg/kg, Arsenic <2.0mg/kg, Mercury <0.1mg/kg). GC-MS tests pesticide residues according to USP and EU guidelines.

Microbiological Testing: Total Plate Count, Yeast/Mold analysis and pathogen screening to confirm the safety of the product.

Each batch includes a Certificate of Analysis (COA) with third-party test reports available upon request.

Payment & Shipment

Payment Terms: T/T (preferred), L/C, Western Union, MoneyGram, PayPal, Visa, MasterCard, Escrow

Shipping Options:

• Express courier: FedEx, DHL, EMS, UPS, TNT (1-5 days for samples)
• Air freight: For medium-volume orders
• Sea freight: Cost-effective for bulk shipments
• Delivery Time: Samples within 1-5 days. Commercial orders are 7-21 working days depending on volume.

We will help you to clear customs in Europe and United States for clients who have no expertise in import and make sure items may be successfully delivered to your factory.

Packaging and Transportation

Standard Packing: 1kg Aluminum foil bag, 5kg carton with double PE bag, 25kg fiber drum with inner PE bag

Storage: Store in cold, dry, light-proof settings below 25°C and relative humidity below 60%.

Custom Packaging: Private label needs ODM/OEM services

Our logistics network covers global destinations with temperature-controlled transportation options for sensitive formulations.

After-sales Service

• 24/7 Technical Support: Professional team addresses formulation questions and application guidance
• Free Samples: Available for quality evaluation before bulk ordering
• Flexible MOQ: Multiple products can be combined in smaller quantities to optimize logistics costs
• Regulatory Support: Documentation assistance for target market compliance submissions
• Quality Guarantee: Batch-specific COAs ensure traceability and consistency

Exhibitions

Attending major international trade shows like Food Ingredients China (FIC), Natural Goods Expo, and SupplySide West is something that we do often. At these events, you will have the opportunity to try out our products for yourself.

Why Choose Us?

Manufacturing Excellence: 2 GMP manufacturing lines with ultrasonic-assisted extraction and macroporous resin adsorption technology assure high yield and stable quality.

Cost Effective. Factory direct price, eliminating the middle man. Bringing warehouses together minimizes the cost of transporting the same item time and time again.

Experience working with people all over the world: We've been working with people in the pharmaceutical, cosmetic, and nutraceutical industries for more than 20 years.

For quality control, there are professional labs with HPLC, ICP-MS, and GC-MS tools. Before being sent out, each batch is carefully checked.

Supply Chain Dependability: To make sure there is a steady supply all year, raw materials come from Sichuan, Shaanxi, Guangxi, and Hubei.

FAQ

Q: How is the consistency of quality between batches?

A: Berberine concentration varies naturally by origin and extraction techniques (2.44-32.96 mg/g). Consistency: We give batch-specific Certificates of Analysis, use standard extraction techniques, and offer parameters such as 10:1, 20:1 ratios or Berberine HCl ≥97% purity.

Q：How long is the lead time?

A: Sample/small orders: Usually 1-5 days following payment confirmation. Commercial bulk orders: Usually 7-21 working days depending on volume and customisation needs.

Q : What is the shipping and packaging?

A：Packaging available in 1kg bags, 5kg cartons, or 25kg fiber drums with inner PE bags. Shipping method is Courier (DHL/FedEx/UPS/TNT), Air freight and Sea freight. Products must be kept in cold dry light-proof settings.

Q：What are the payment terms?

A：T/T is most common. We also accept L/C, Western Union, MoneyGram, and Alibaba Secure Payment for your convenience.

Contact Us

Ready to enhance your formulations with premium Phellodendron Extract? Contact our sales team at sales@jayuanbio.com and sales1@jayuanbio.com  for quotations, samples, or technical specifications.