Pyrroloquinoline Quinone Disodium Powder - Premium Mitochondrial Biogenesis Activator for Functional Nutrition Solutions
Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with a registered capital of RMB 30 million, specializes in producing high-purity Pyrroloquinoline Quinone Disodium through advanced bacterial fermentation technology. Our PQQ-2Na has continuously provided ≥99.0% purity (HPLC) and remarkable redox cycling capabilities, catalyzing up to 20,000 reactions before depletion. We have 2 GMP standard manufacturing lines, ISO9001, SGS, HALAL certifications, and the monthly capacity of 500-1000kg with assured in-stock availability. This dark red fine powder delivers 5,000x higher antioxidant effectiveness than Vitamin C, addressing industry concerns of ingredient stability and bioavailability for your cognitive support and cellular energy formulations.
What Is Pyrroloquinoline Quinone Disodium?
The product (PQQ-2Na) is the stabilized, water-soluble salt version of Pyrroloquinoline Quinone, a revolutionary redox cofactor, classed as a longevity vitamin contender. This disodium version has better bioavailability and formulation stability than the free acid form.
Your formulations benefit from the unique capacity of this new chemical to activate mitochondrial biogenesis via PGC-1α pathway activation. Our industrially fermented form of the molecule is naturally present in trace levels in kiwi and parsley and assures constant bio-identity and pharmaceutical-grade purity.
The substance is GRAS in the USA and is Novel Food approved in the EU therefore there are no regulatory hurdles for your product development. It differs from hydrophobic PQQ acid in its high water solubility, making it easy to incorporate into various delivery forms.
COA
| Product Name | Pyrroloquinoline Quinone Disodium | ||
| Lot No | 240401 | Quantity | 400kg |
| Manufacture Date | 2024.05.06 | Expiry Date | 2026.05.05 |
| CAS | 122628-50-6 | ||
| COUNTRY OF ORIGIN | China | ||
| MOLECULAR FORMULA | C14H4N2NA2O8 | ||
| Ref standard | According with the IHS standard | ||
| Items | Requirements | Results | |
| Appearance | Fine powder | Conforms | |
| Color | Reddish orange to reddish brown | Conforms | |
| Taste | Salty | Conforms | |
| Identification | Positive match with standard | Conforms | |
| Assay(Dry basis) | ≥98.0% | 99.60% | |
| Loss on drying | ≤12.0% | 8.5% | |
| Heavy metal | ≤10ppm | Conforms | |
| Arsenic (As) | ≤1.5ppm | Conforms | |
| Cadmium(Cd) | ≤0.3ppm | Conforms | |
| Lead(Pb) | ≤1.0ppm | Conforms | |
| Mercury(Hg) | ≤0.20ppm | Conforms | |
| Residual solvent | Ethanol≤5000ppm | Conforms | |
| Total Plate Count | ≤1000cfu/g | Conforms | |
| Mold &Yeast | ≤100 cfu/g | Conforms | |
| Enterobacteriaceae | ≤100 cfu/g | Conforms | |
| E. Coli | Negative | Conforms | |
| Salmonella | Negative/10G | Conforms | |
| Staphylococcus aureus | Negative | Conforms | |
| Conclusion | The product conforms to the IHS standard | ||
Functions
Your product formulations gain multiple functional advantages with our PQQ-2Na. The chemical stimulates Nerve Growth Factor (NGF), providing direct support to cognitive function and neuroprotection. Its redox cycling mechanism enables it to provide continuous antioxidant defense, with extraordinary efficacy in neutralizing reactive oxygen species.
Mitochondrial biogenesis stimulation represents the core functional benefit. Your customers experience enhanced cellular ATP production, addressing energy metabolism at the foundational level. This mechanism proves particularly valuable for aging populations experiencing mitochondrial decline.
The ingredient's ability to improve insulin sensitivity and optimize lipid metabolism positions your formulations within the expanding metabolic health category. Its thermal stability up to moderate processing temperatures ensures manufacturing flexibility across production methods.
Application Fields
Advanced Nootropic Formulations
Combine our Pyrroloquinoline Quinone Disodium with CoQ10 and Phosphatidylserine to create synergistic cognitive support stacks. The NGF upregulation specifically targets age-related cognitive decline, memory enhancement, and mental clarity applications.
Sports Nutrition & Recovery Solutions
Your performance nutrition products benefit from PQQ-2Na's capacity to manage exercise-induced oxidative stress and lactate accumulation. Its water solubility enables incorporation into functional beverages, pre-workout powders, and post-exercise recovery formulations requiring rapid absorption.
Metabolic Health & Longevity Products
Deploy this ingredient in anti-aging protocols targeting mitochondrial efficiency. Softgel formulations achieve optimal lymphatic absorption when suspended in lipid carriers, while capsule formats leverage its excellent powder flow characteristics.
Quality Control
All stages of manufacturing are subject to our quality assurance system. We have competent analytical labs to do thorough testing, including HPLC purity analysis, heavy metal screening, residual solvent testing and microbiological testing.
Each batch goes through rigorous spectroscopic techniques of identification verification. We measure thermal stability parameters and maintain regulated storage conditions to retain redox potential over shelf life.
Third party testing verifies our own quality processes. You obtain comprehensive paperwork including Certificates of Analysis, batch production records and stability data to support your regulatory applications.
Certificates
We are ISO9001 Quality Management System certified, which guaranties continual manufacturing excellence. We are GMP compliant in both manufacturing lines as per international pharmaceutical standards.
SGS verification and HALAL certification expand your market access across diverse geographical regions. As a recognized High-tech Enterprise of Shaanxi Province, we demonstrate ongoing innovation commitment in natural ingredient biotechnology.
Payment & Shipment
We accept flexible payment terms including T/T, L/C, and PayPal arrangements based on order volume. Our established partnerships with FedEx, DHL, EMS, UPS, and TNT ensure reliable global delivery.
For customers new to importing, we provide customs clearance assistance in Europe and the United States. Your products reach your facility directly, minimizing logistics complexity and reducing clearance delays.
Air freight delivers samples and small orders within 5-7 business days. Larger shipments utilize ocean freight for cost optimization, with full container loads available for volume purchasers.
Packaging & Transportation
Standard packaging includes moisture-proof foil bags for 1kg quantities and fiber drums with double polyethylene bags for 25kg bulk orders. This multilayer protection preserves hygroscopic powder integrity during transit.
Your custom packaging requirements receive accommodation for private label projects. We implement light-protective materials addressing UV sensitivity concerns inherent to Pyrroloquinoline Quinone Disodium.
Temperature-controlled logistics provide product stability throughout climatic zones. Our packaging meets international shipping rules to enable safe handling across the whole supply chain.
After-sales Service
Our technical support team provides formulation guidance addressing solubility optimization, dosage recommendations, and stability enhancement strategies. You receive ongoing consultation throughout product development cycles.
We maintain buffer stock ensuring rapid response to reorder requirements. Quality concerns trigger immediate investigation with replacement shipments expedited at our expense when warranted.
We provide comprehensive documentation assistance including regulatory dossiers, safety data sheets and formulation case studies. We want to make sure we have a long-term collaboration success, not just close a deal.
Exhibitions
Xi'an Jiayuan Bio-tech is often engaged at the main international trade fairs including Supply Side West, Vitafoods Europe and FI Asia. These displays provide the opportunity for face-to-face discussion of your individual application needs.
Visit our booth to examine product samples, review technical documentation, and explore collaborative development possibilities. Our exhibition presence demonstrates industry leadership and commitment to transparent customer relationships.
Why Choose Us?
Direct Manufacturer Advantage
Eliminate intermediary markups with factory-direct pricing. Our integrated production facility controls costs while maintaining quality standards, delivering superior value for your procurement budget.
Flexible Order Quantities
Start with our 1kg minimum order for formulation trials. Scale seamlessly to bulk quantities as your product launches, with consistent quality across order sizes ensuring smooth commercialization.
Comprehensive Service Integration
Beyond raw material supply, we offer formulation consulting, regulatory support, and logistics coordination. This integrated approach reduces your operational complexity and accelerates time-to-market.
Proven Manufacturing Excellence
Two decades of natural extract expertise backs every shipment. Our 30-person technical team combines fermentation biotechnology knowledge with quality assurance rigor, ensuring reliable supply continuity.
FAQ
Q: What is the difference between PQQ acid and the product?
A: Poor water solubility and bioavailability of the free acid may be improved by using the disodium salt. This means improved formulation stability and higher absorption in the end product and is the ideal criterion for dietary supplements.
Q: How much PQQ-2Na should be taken in supplements?
A: The standard doses for cognitive and mitochondrial support are 10-20mg daily. Target and formulation delivery format can impact appropriate dosage for your individual formulation. Our technical staff is here to help and guide you based on published clinical studies and formulation expertise.
Q: How should PQQ Disodium be stored?
A: Store in airtight containers, protected from light, moisture and heat. Optimal circumstances are temperatures below 25 °C and relative humidity below 60 %. Proper storage preserves the redox potential of the chemical and offers shelf-life stability of up to 24 months from the date of manufacturing.
Q: Is PQQ-2Na vegetarian or vegan-friendly?
A: Yes, our PQQ Disodium produced by fermentation is free of any animal originated substances. It complements plant-based capsule shells and meets vegan certification standards, thus, extending your accessible market segments.
Q: Can you provide samples for formulation testing?
A: We provide 50-100g samples for approved clients. Examples of inquiries include basic application information to determine the appropriate technical support. Samples ship within 48 hours after approval to support quick formulation development cycles.
Q: What documentation do you provide for regulatory submissions?
A: Each order comes with Certificate of Analysis, batch production records, allergy statements, GMO declarations, BSE/TSE certifications and country-of-origin paperwork. Additional regulatory support documents are available on request for FDA, EFSA or other authority submissions.
Contact Us
Ready to enhance your formulations with premium-grade Pyrroloquinoline Quinone Disodium? Our technical specialists at sales@jayuanbio.com and sales1@jayuanbio.com provide rapid quotations, sample coordination, and application support.
