NMN β-Nicotinamide Mononucleotide | High-Purity NAD+ Precursor for Longevity & Metabolic Health Solutions
Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with RMB 30 million registered capital, delivers pharmaceutical-grade nmn β-nicotinamide mononucleotide through two GMP-certified production lines. Enzymatic synthesis route enables us to manufacture 10 tons/month with ≥99% purity and unique Beta-anomer stereospecificity. ISO9001, HALAL, KOSHER CERTIFIED We offer direct manufacturer pricing, formulation change and worldwide delivery via FedEx, DHL and UPS. Our 30-person workforce conducts quality control from raw material selection to final inspection to worldwide nutritional supplement, cosmeceutical and pharmaceutical standards.
What Is NMN β-Nicotinamide Mononucleotide?
Bioactive nucleotide 1094-61-7 contains nicotinamide, ribose, and phosphate.
It overcomes the commercial dilemma of the NAD+ Bioavailability Paradox by being the most direct precursor to NAD+. NAD+ levels drop 50% with age, however direct replenishment doesn't work since it doesn't enter cells.
Our material overcomes this obstacle by swiftly replenishing intracellular NAD+ reserves via Slc12a8 transporters. This boosts mitochondrial activity, metabolic regulation, and DNA repair via Sirtuins (SIRT1-7).
Our Beta-anomer formulation has better bioavailability for longevity and metabolic health applications than precursors Nicotinic Acid or Nicotinamide, which are rate-limiting enzymes.
COA
| Product Name | β-Nicotinamide Mononucleotide(NMN) | ||
| Lot No | 240309 | Quantity | 320kg |
| Test Date | 2024.04.11 | Expiry Date | 2026.04.10 |
| Ref standard | According with the interprise standard | ||
| Items | Requirements | Results | |
| Appearance | White to off-White powder | Conforms | |
| Assay（HPLC) | ≥98% | 99.70% | |
| pH(1% of aqueous) | 2.0-4.0 | 3.3 | |
| Clarity | Solution should be clarify,none suspended matters | Conforms | |
| Loss on drying | ≤1.0% | 0.12% | |
| Chlorides ppm | ≤200 | ＜200 | |
| Mesh size/mesh | ≥40 | ＞40 | |
| Redidual solvents(Ethanol) | ≤500 | ＜500 | |
| Bulk density g/ml | ≥0.15 | ＞0.15 | |
| Heavy metal ppm | ≤2 | 0.5 | |
| Arsenic ppm | ≤0.5 | ＜0.5 | |
| Total Plate Count | ＜750cfu/g | ＜10cfu/g | |
| Yeast&Mold | ＜50cfu/g | ＜10cfu/g | |
| E.Coli | ＜3 MPN/g | Negative | |
| S.Aureus | Negative | Negative | |
| Salmonella | Negative | Conforms | |
| Conclusion | The product conforms to the interprise standard | ||
Core Functions
Your formulations gain from the established biologically active properties of our material:
Restoring NAD+: Bypasses limits of the NAMPT enzyme to directly raise intracellular NAD+ levels, aiding cellular energy metabolism.
Mitochondrial Support: Improves ATP generation efficiency to optimise age-related mitochondrial dysfunction in metabolic health products.
DNA Repair Activation: Boosts PARP enzymes for genomic stability, a key feature of anti-aging supplement formulas.
Sirtuin Pathway Activation: Activates SIRT1-7 proteins to control lifespan and stress resistance-related gene expression.
Application Fields
Advanced Dietary Supplements: Formulate nmn β-nicotinamide mononucleotide enteric-coated capsules or sublingual tablets to guard against breakdown by stomach acid. It guarantees the best absorption via intestinal transporters for goods of lifespan and metabolic health.
Synergistic Combinations: Use with Resveratrol, PQQ or CoQ10 in liposomal delivery methods. Our material’s chemical stability characteristics permits it to be included into sophisticated multi-ingredient supplements aimed at cellular energy and cognitive function.
Cosmeceutical Applications: Use in high-end anti-aging formulas for topical NAD+ boost to help repair skin DNA and rejuvenate cells. Aqueous formulations need particular stabilisation measures to avoid hydrolysis.
Quality Control System
We have two GMP standard manufacturing lines with multi-stage quality inspection.
Supplier checks and certificate verification to verify pharmaceutical quality starting materials. Raw Material Screening
In-Process Monitoring: Real-time HPLC analysis ensures Beta-anomer purity at all synthesis stages, free from inactive Alpha-anomer contamination.
Stability Testing: Shelf-life claims are confirmed by accelerated ageing experiments conducted under controlled circumstances of temperature and humidity.
Microbial & Heavy Metal Testing: Each batch is thoroughly tested for safety to USP and EP standards with endotoxin control < 0.5 EU/mg.
Certificate of Analysis: Every shipment is provided with complete documentation including purity, stereospecificity (by Polarimeter/NMR) and solvent residue analysis.
Certifications & Compliance
- ISO9001 Quality Management System (certified 2012)
- ISO22000 Food Safety Management
- HALAL & KOSHER certifications for global market access
- BRC Global Standard for Food Safety
- ORGANIC certification for natural product lines
- Recognized as Shaanxi Province High-tech Enterprise (2013)
Payment & Shipment
Payment Terms T/T,L/C,Western Union,and customised terms for long-term partners.
Global Logistics Network : We collaborate with FedEx, DHL, EMS, UPS, TNT for delivery in 5-10 business days to key markets. Temperature controlled shipping to ensure product integrity during transportation.
Customs Support. We offer paperwork support and clearance support in Europe and North America, at your location, for customers with no import expertise.
Packaging & Transportation
Standard Packaging: Aluminium foil bags, 1 kilogram. Fibre drums, 25 kg. Double layer PE inside bags. Or as per your needs.
Temperature Control: Cool-chain logistics minimise heat-induced hydrolysis in the summer months, retaining potency throughout transport.
Documentation : CoA, MSDS, packing list and business invoice available for easy customs clearance on each shipment.
After-sales Service
nmn β-nicotinamide mononucleotide Your Success Is Our Motivation:
Technical Consultation: Our R&D team offers formulation advice, stability suggestions and dose optimisation assistance.
Sample Policy Free samples (10-50g) offered for approved B2B partners to test material compatibility.
Quality Guarantee: If any material does not reach the specified requirement, we will provide a complete replacement or refund within 30 days of delivery.
Ongoing Support: Post delivery support for formulation issues, regulatory queries and incorporating market input.
Exhibitions
Attending major international trade shows like Food Ingredients China (FIC), Natural Goods Expo, and SupplySide West is something that we do often. At these events, you will have the opportunity to try out our products for yourself.
Why Choose Xi'an Jiayuan Bio-tech?
Direct Manufacturer Prices: Buy straight from the manufacturer, cut out the middleman markups and reduce your formulation expenses up to 30%.
Proven Production Scale: With a monthly capacity of 10 tonnes, we can guarantee a consistent supply for developing brands, and our flexible MOQs can cater to startups and established organisations alike.
Benefits of Biological Enzyme Synthesis: Our biological enzyme technique provides greater Beta-anomer purity than chemical synthesis with lower residual solvents and consistent batch-to-batch quality.
One-Stop Sourcing: Choose from our extensive product catalogue for a range of natural ingredients, and consolidate shipments to save on transportation and streamline customs.
20+ Years of Industry Experience: Since 2002 we have serviced 800+ worldwide customers in 50+ countries and built confidence via constant quality and quick service.
FAQ
Q: How is the synthetic product different from enzymatic product?
A: Enzymatic synthesis is to use biological enzyme to imitate the natural production, thus it has greater purity, specific Beta-conformation and less solvent residue than chemical synthesis, which may generate mixed anomers.
Q: How does temperature influence the stability of the product during transportation?
A: NMN is susceptible to heat. Prolonged exposure to temperatures over 25°C may increase the rate of hydrolysis to Nicotinamide. Cool-chain or temperature-controlled shipment is required to ensure potency for professional logistics.
Q: Can the product be used with water to make liquid drinks?
A: NMN is very soluble yet it is not stable in liquid for a long time (degrades quickly). RTD drinks need unique capping technologies or fresh-mixing designs to keep the powder separate until the consumer wants to use it.
Q: How do you know that the NMN is indeed the Beta-anomer?
A: Normal HPLC will tell you purity, but not necessarily stereochemistry. Presence of bioactive Beta-form alone must be confirmed using a Polarimeter test (Specific Rotation) or NMR analysis.
Q: What is the safe dose range now?
A: Typically human clinical studies use doses of 250mg to 900mg per day. B2B formulations are often 300mg to 500mg units to ensure cost efficiency and efficacy.
Contact Us
Ready to enhance your product line with premium nmn β-nicotinamide mononucleotide? Contact our team at sales@jayuanbio.com and sales1@jayuanbio.com for quotations, samples, and technical support today.
