What is Stigmasterol?

Stigmasterol is a plant sterol, also known as a phytosterol. It is a natural compound found in the fatty tissues of plants. Structurally, it resembles cholesterol in animals. Stigmasterol is known for its role in the synthesis of hormones and has been studied for its potential health benefits.

As an active ingredient, stigmasterol powder is widely used in pharmaceuticals, cosmetics, and dietary supplements.

Stigmasterol Powder

Stigmasterol Structure

Stigmasterol is a white, crystalline substance with the chemical formula C29H48O. Its structure is similar to that of cholesterol, featuring a sterol backbone with a double bond in the steroid nucleus and a methyl group at the carbon-24 position. This unique structure gives it its biological activity and its ability to interact with cellular membranes and enzymes in the human body.

What Type of Lipid is Stigmasterol?

Stigmasterol is a type of lipid known as a phytosterol. Phytosterols are plant-derived sterols that are structurally similar to cholesterol. They are essential components of plant cell membranes, just as cholesterol is in animal cell membranes. Phytosterols like stigmasterol are hydrophobic molecules, which means they do not mix well with water and are typically found in the fatty parts of plants.

Does Stigmasterol Lower Cholesterol?

Research suggests that stigmasterol may help lower cholesterol levels. Like other phytosterols, it competes with dietary cholesterol for absorption in the digestive system. This competition can reduce the overall absorption of cholesterol, leading to lower blood cholesterol levels. Some studies have shown that the inclusion of phytosterols in the diet can reduce LDL cholesterol (the "bad" cholesterol) by up to 10%.

What is Stigmasterol Used For

Stigmasterol is used for a variety of purposes. In the pharmaceutical industry, it is utilized for its anti-inflammatory and cholesterol-lowering properties. It is also a precursor in the synthesis of steroid hormones and vitamin D. In cosmetics, stigmasterol is valued for its skin-conditioning benefits and is used in creams and lotions. Additionally, it is used in dietary supplements aimed at improving heart health and reducing cholesterol levels.

What is Stigmasterol Composed Of?

Stigmasterol is composed of carbon, hydrogen, and oxygen atoms, forming a sterol structure. Its molecular composition is C29H48O, and it features a hydroxyl group at the 3-beta position, a double bond at the 5,6 position, and a side chain at the 17 position.

These structural features are crucial for its biological activity and its ability to interact with cell membranes and enzymes.

What is the Source of Stigmasterol?

Stigmasterol is found in a variety of plant sources. Common sources include soybeans, vegetable oils, nuts, seeds, and green leafy vegetables. It can also be extracted from certain medicinal plants like Strophanthus gratus and various species of the Solanum genus. The extraction process typically involves solvent extraction followed by purification steps to obtain high-purity Stigmasterol powder.

What is Phytosterol Complex?

A phytosterol complex is a mixture of different plant sterols, including stigmasterol, beta-sitosterol, and campesterol. These complexes are often used in dietary supplements and functional foods to promote heart health by lowering cholesterol levels. Phytosterol complexes take advantage of the synergistic effects of multiple sterols, providing a broader range of health benefits compared to individual sterols alone.

Stigmasterol Benefits

Stigmasterol offers several health benefits:

· Cholesterol Reduction: As mentioned, stigmasterol can lower LDL cholesterol levels by inhibiting its absorption in the intestines.

· Anti-inflammatory Properties: Stigmasterol has been shown to reduce inflammation, making it beneficial for conditions like arthritis.

· Antioxidant Effects: It acts as an antioxidant, protecting cells from damage caused by free radicals.

· Hormone Synthesis: Stigmasterol is a precursor for the synthesis of important hormones such as progesterone.

· Immune Support: It has been found to enhance the immune system, aiding in the body’s defense against infections.

Contact us for a free sample of our premium Stigmasterol powder to experience these benefits firsthand.

Stigmasterol Side Effects

While stigmasterol is generally considered safe, some potential side effects should be noted:

· Gastrointestinal Issues: High doses may cause digestive discomfort, including nausea, diarrhea, and constipation.

· Allergic Reactions: Rarely, individuals may experience allergic reactions, presenting as rashes or itching.

· Drug Interactions: Stigmasterol may interact with cholesterol-lowering medications, enhancing their effects and potentially leading to excessively low cholesterol levels.

It is always advisable to consult with a healthcare professional before starting any new supplement regimen.

Stigmasterol Powder


What is the recommended dosage of stigmasterol extract powder?

The recommended dosage varies based on the intended use. For cholesterol reduction, doses of 1.5 to 3 grams per day are common. However, it is best to follow the dosage instructions provided by a healthcare professional or the product manufacturer.

Can stigmasterol be taken with other supplements?

Yes, stigmasterol can be taken with other supplements. However, it is important to ensure that there are no interactions with other supplements or medications you may be taking. Consulting a healthcare professional is recommended.

Is stigmasterol suitable for vegetarians and vegans?

Yes, stigmasterol is plant-derived and suitable for vegetarians and vegans.

How should stigmasterol be stored?

Stigmasterol should be stored in a cool, dry place, away from direct sunlight and moisture. Proper storage conditions will help maintain its stability and effectiveness.

What forms does stigmasterol come in?

Stigmasterol is available in various forms, including Stigmasterol powder, capsules, and tablets.


Stigmasterol is a versatile and beneficial phytosterol with a range of applications in health, cosmetics, and pharmaceuticals. Its ability to lower cholesterol, reduce inflammation, and support hormone synthesis makes it a valuable ingredient in many products.

At Xi'an Jiayuan Bio-tech Co., Ltd., we pride ourselves on being a leading manufacturer and supplier of high-quality Stigmasterol powder. Our commitment to quality, safety, and customer satisfaction ensures that you receive the best products for your needs.

Contact us at sales@jayuanbio.com for a free sample to discover the benefits of our premium Stigmasterol powder. For more information or to place an order, please reach out to us at sales@jayuanbio.com.


1. "Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses." Comprehensive Reviews in Food Science and Food Safety.

2. "Functional Foods: The Connection Between Nutrition, Health, and Food Science." Academic Press.

3. "Phytosterols and cardiovascular health." OCL - Oilseeds and fats, Crops and Lipids.

4. "Dietary Phytosterols: A Review of Metabolism, Benefits, and Side Effects." Life Sciences.

5. "Chemistry and biochemistry of plant sterols." In Phytochemistry of fruits and vegetables.