Honokiol Powder

High-Purity Honokiol Powder Extract | 98% GC-Tested Pharmaceutical Grade for Advanced Research & Supplement Manufacturing

Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with RMB 30 million registered capital, delivers pharmaceutical-grade Honokiol Powder extracted from Magnolia officinalis bark through proprietary solvent extraction and recrystallization technology. Our product has ≥98% purity validated by GC/HPLC analysis, with 2 GMP-standard manufacturing lines and ISO9001/HALAL/KOSHER certificates. We have a staff of 80, including 30 technologists, and we provide batch-consistent bioactive ingredients for pharmaceutical R&D, nutraceutical formulation and advanced research applications to the worldwide marketplace.

What Is Honokiol Powder?

This substance is a bioactive biphenolic molecule isolated from the bark of Magnolia officinalis, and is known for its outstanding pharmacological profile. It is a white crystalline powder with molecular formula C18H18O2 and CAS NO. 35354-74-6 and solves major formulation problems in the natural product business.

This compound solves three major pain points. First, it has research-grade purity (≥98%) without batch variation problems seen in crude extracts. Secondly, its multi-target pharmacology provides single ingredient treatments for the pathways of inflammation, oxidative stress and neuroprotection. Third, it qualifies for orphan drug status in the U.S., which enables enhanced pharmaceutical development.

We provide parameters from 50%-90% total phenol to 98% pure Honokiol with comprehensive traceability from raw material procurement to final product release.

COA 

Product Name	Honokiol Powder
Ref standard	Enterprise standard
Items	Requirements	Results	Method
Appearance	White powder	Conforms	Visual
Odor	Unique smell of Magnolia Bark	Conforms	Organoleptic
Taste	Unique taste of Magnolia Bark	Conforms	Olfactory
Bulk Density	Slack Density	0.37g/100ml	USP616
	Tight Density	0.61g/100ml	USP616
Particle Size	95%Through 80 Mesh	Conforms	CP2015
Honokiol	≥98.0%	98.29%	HPLC
Moisture	≤1.0%	0.20%	CP2015 (40 oC, 4 h)
Ash	≤1.0 %	0.40%	CP2015
Total Heavy Metals	<10 ppm	Conforms	CP2015
Aerobic Bacterial Count	≤1,000 CFU/g	Conforms	GB4789.2
Yeast	≤100 CFU/g	Conforms	GB4789.15
Mold	≤100 CFU/g	Conforms	GB4789.15
Escherichia Coli	<3.0MPN/g	Conforms	GB4789.38
Salmonella	Not Detected	Conforms	GB4789.4
Staphlococcus Aureus	Not Detected	Conforms	GB4789.10
Conclusion	The product conforms to the enterprise standard

Functions

Pharmacological Activity	Mechanism of Action
Antitumor	Induces apoptosis in cancer cells through mitochondrial pathways
Anti-inflammatory	Inhibits NF-κB signaling cascade and pro-inflammatory cytokines
Neuroprotective	Modulates GABA-A receptors; reduces neuroinflammation
Antioxidant	Scavenges free radicals; upregulates endogenous antioxidant systems
Antibacterial	Disrupts bacterial cell membrane integrity
Corneal Repair	Promotes epithelial wound healing through growth factor modulation

The molecule has better bioavailability as compared to regular polyphenols, ensuring efficient distribution in low dosage formulations.

Application Areas

Honokiol Powder is used in three major commercial segments that are a convergence of performance and compliance:

Pharmaceutical R&D: Development of Investigational New Drug (IND) applications in cancer and neurological illnesses. Its orphan drug status fast-tracks regulatory routes for treatments of uncommon diseases.

Nutraceutical Manufacturing: Stress reduction, sleep aid and cognitive health products encapsulated in hard-shell capsules and enteric coated tablets. The powder is stable and may be encapsulated at high speed without flow agent additions.

Research Reagents: Available to university and commercial labs for research on inflammatory biology, mitochondrial function and receptor pharmacology. Solution stability of 1 month at 0–4°C allows various experimental techniques to be performed from single batches.

Quality Assurance

There are six important control points for quality assurance throughout the whole chain. Botanical identification verification of raw materials using morphological and chemical fingerprinting. Extraction monitoring measures parameters of solvent purity and temperature. Monitoring of crystallisation during purification steps in real time.

Finished product is tested for ≥98% purity by GC or HPLC, melting point measurement, moisture content (<5%) and residual solvent screening. - Every batch is accompanied by a complete Certificate of Analysis with 12+ physicochemical parameters. Our traceability technology cross-references raw material lot numbers with completed product batches for full transparency throughout the supply chain.

Professional laboratory teams conduct quarterly method validation and participate in interlaboratory comparison programs to maintain measurement accuracy.

Certificates

• ISO9001 Quality Management System
• FSSC22000 Food Safety System
• HALAL Certification
• KOSHER Certification
• HACCP System Certification
• Private Science and Technology Enterprise (Shaanxi Province)
• High-tech Enterprise (Shaanxi Province)

Payment & Shipment

Payment Terms: T/T (standard), with L/C, D/P, PayPal, MoneyGram, and Western Union available through negotiation.

Logistics Network: We partner with FedEx, DHL, EMS, UPS, TNT, international airlines, and shipping companies for global delivery. For clients lacking import experience, we offer customs clearance support in European and American markets, delivering directly to your facility.

Lead Time: Standard MOQ of 1 kg of Honokiol Powder ships within 7–15 business days. Urgent orders can be expedited to 3–5 business days based on inventory status.

Packaging & Transportation

Standard packaging includes 1 kg aluminum foil bags and 25 kg fiber drums with food-grade inner liners. Custom packaging configurations available upon request for branded distribution or specific machinery compatibility.

Ship at ambient temperature with light and moisture protection. No cold chain required, reducing logistics costs. Products remain stable during standard international shipping durations when stored in sealed containers away from direct sunlight.

After-sales Service

Upon request we may offer samples for formulation testing and compatibility studies. Complete paperwork packages including COA, SDS, and Certificate of Origin for regulatory submissions Technical support teams will be available to help with formulation assistance, stability testing suggestions and regulatory compliance queries.

Custom Specifications ODM/OEM Services Private Labelling, Co-Manufacturing Arrangements Available Note: We do not sell retail amounts to individuals.

Why choose us?

Factory-Direct Price: We are a direct factory with 2 GMP manufacturing lines, no intermediary markup and affordable prices for large orders.

Batch Consistency Guaranty - Our quality methods control batch-to-batch purity fluctuation to within ±1%. This is crucial for clinical studies and for the stability of supplement formulation.

Flexible MOQ : Buy numerous botanical extracts in lesser amounts to decrease inventory cost and storage cost. Consolidated shipping cuts logistical expenses even further.

Worldwide Compliance Knowledge: Over 20 years of export expertise, independent import/export rights, and an understanding of foreign laws including FDA, EFSA and customs paperwork needs.

FAQ

Q: How do you ensure batch-to-batch quality consistency? What specifications do you follow? Can you provide a complete COA for each batch?

A：We implement strict quality control from raw material to final product, adhering to purity specifications such as ≥98% (by GC or HPLC). Each batch is accompanied by a complete COA covering purity, appearance, melting point, moisture, and residual solvents to ensure batch-to-batch consistency.

Q: What is the MOQ and lead time? Can you handle urgent orders?

A：Standard MOQ is 1 kg. Regular orders are delivered within 7–15 business days. For urgent orders, we can expedite shipment to 3–5 business days depending on stock availability.

Q: What packaging options are available? Are there special shipping requirements? Who manages customs clearance?

A：We offer packaging such as 1 kg/aluminum foil bag and 25 kg/cardboard drum, with customization available upon request. Ship at ambient temperature, protected from light and moisture; no cold chain is required. We provide full export documentation, but import clearance is the buyer's responsibility.

Q: What payment terms are accepted?

A：We primarily accept T/T as the standard method. L/C, D/P, PayPal, MoneyGram, and Western Union are also negotiable.

Contact Us

Ready to source pharmaceutical-grade Honokiol Powder for your next formulation? Contact our technical team at sales@jayuanbio.com and sales1@jayuanbio.com for COA samples and custom quotations today.