Everything You Need to Know About Cytisine: Uses, Benefits, and More
When it comes to plant-based alkaloids that may help smokers quit the habit, cytisine powder is among the most encouraging. Many people in the pharmaceutical and nutraceutical sectors are interested in this naturally occurring chemical, which comes from the broom plant (Cytisus scoparius) and the golden chain tree (Laburnum anagyroides). The unique features of cytisine make it an attractive non-nicotine alternative in many contexts, including research and nutritional supplements. Researchers and producers may fully exploit it to build smoking cessation medicines if they learn how to use it appropriately and understand all of its ins and outs.

Product Name: Cytisine 98%
CAS NO.: 485-35-8
Molecular formula: C11H14N20
Molecular weight: 190.24
Specification content: 98%(HPLC)
Product Description: Diagonal Prism Powder
Physical properties: Melting point of 98-99 ℃, soluble in water, ethanol, methanol, insoluble in petroleum ether.
MOQ: 500gG-1KG
Our Advantages: Scalable production capacity, strict quality control, cost efficiency from integrated factories, over 20 years of experience, advanced technology, and 24/7 after-sales support.
Certificaions: FSSC2000/ISO2000/HALAL/KOSHER/HACCP
Delivery terms: FedEx, DHL, EMS, UPS, TNT, all kinds of the airline, international shipping companies.
Payment: TT/DP/PAY PAL/VISA/DA/LC/MASTER CARD/ESCROW
Grade: Cosmetics Grade, Food Grade, Pharmaceutical Grade
Customized Service: Supports ODM/OEM
Free sample is available.
We do not sell retail quantities to individuals.
Key Parameters and Quality Indicators of Cytisine
Core Quality Specifications
High-quality cytisine powder requires strict adherence to specific parameters that determine its effectiveness and safety. The purity level stands as the most critical indicator, with pharmaceutical-grade products typically maintaining ≥99% purity levels. This alkaloid appears as a white to off-white crystalline powder with a molecular formula of C11H14N2O and a molecular weight of 190.24 g/mol.
Stability Indicators and Physical Characteristics
Moisture substance control remains basic for product stability. Premium cytisine powder keeps up dampness levels ≤0.5%, which extends rack life past three a long time when appropriately stored. The softening point ranges between 152-158°C, serving as another quality confirmation strategy. Dissolvability characteristics appear to show great disintegration in water and ethanol, making it appropriate for different detailing types.
Analytical Testing and Quality Assurance
Advanced testing strategies, including HPLC and GC-MS, guarantee compliance with EP/USP pharmacopoeia benchmarks. These expository methods confirm the absence of overwhelming metals, remaining solvents, and microbial contamination. Quality producers execute real-time checking utilizing near-infrared spectroscopy during production to maintain steady clump quality.
Core Benefits and Mechanisms of Action
Receptor Interaction and Mechanism
Cytisine capacities as a fractional agonist at nicotinic acetylcholine receptors, particularly focusing on α4β2 neuronal receptors. This instrument makes a difference in decreasing nicotine desires while minimizing withdrawal side effects related to smoking cessation endeavors. Not at all like nicotine substitution treatments, this plant extract gives a gentler approach to breaking tobacco enslavement patterns.
Pharmacological Advantages
The alkaloid illustrates momentous receptor authoritative fondness, effectively blocking nicotine's fulfilling impacts while activating direct dopamine discharge. This double activity makes a difference in keeping up neurochemical adjust amid the move absent from tobacco utilize. Clinical ponders show that cytisine may decrease smoking inclinations within the to begin with week of supplementation.
Broader Therapeutic Potential
Research proposes this homegrown cure offers focal points over manufactured options like varenicline. Its normal beginning and shorter half-life contribute to fewer side effects and superior resistance among clients. The compound's pharmacology profile appears to have quick assimilation and disposal, lessening the hazard of amassing in body tissues. Past smoking cessation efforts, cytisine illustrates potential benefits for cognitive function improvement, with a few studies demonstrating support for neurotransmitter adjustment and sound stretch response patterns.
Jiayuan Bio-Tech's Premium Cytisine Powder vs. Competitors
Extraction and Purification Advantages
Jiayuan Bio-Tech's cytisine powder is recognized through predominant extraction forms and quality control measures. The energetic countercurrent extraction strategy accomplishes 30%-50% higher proficiency compared to conventional submersion methods, while diminishing dissolvable utilization and maximizing dynamic compound surrender. The recreated moving bed chromatography decontamination framework empowers continuous generation with steady performance over 98%, dodging the irregularities common in clump handling. A mechanized DCS framework absolutely controls pH, temperature, and dsoluble proportions, guaranteeing extraordinary group consistency and minimizing human error.
Cost Efficiency and Sustainability
Cost focal points emerge from comprehensive crude material utilization, permitting synchronous extraction of extra important compounds and bringing down the overall production costs. The dissolvable recuperation framework accomplishes ≥90% ethanol recuperation, essentially decreasing consumables compared to industry standards. Quality affirmation surpasses commonplace guidelines through double testing conventions utilizing both online observing and offline HPLC and GC-MS investigation, supported by GMP and ISO 13485 certifications. Natural obligation assists Jiayuan Bio-Tech through zero fluid release wastewater treatment and squander composting programs, guaranteeing economical generation with nearby competitive pricing.
Optimal Usage Guidelines and Applications
Industry Applications
Cytisine powder finds applications in different businesses, each requiring particular utilization considerations. Pharmaceutical companies incorporate it into smoking cessation tablets and capsules, regularly combining it with behavioral treatment programs for improved efficacy. The standard dose ranges from 1.5mg to 9mg day by day, depending on the definition requirements. Nutraceutical producers mix cytisine with complementary fixings such as passionflower extricate or L-theanine to make broader smoking cessation products, and its unbiased taste profile suits tablets, capsules, and fluid preparations. Inquire about education depends on high-purity cytisine for pharmacological ponders and receptor authoritative investigate, requiring detailed certificates of analysis, stability information, and appropriate storage in cool, dry conditions secured from light.
Manufacturing and Quality Considerations
Manufacturing considerations incorporate compatibility with common excipients and preparation helps, as cytisine illustrates great stability during granulation, compression, and encapsulation. In any case, introduction to extraordinary warm or humid conditions ought to be avoided. Quality control testing guarantees consistency over the supply chain, from crude fabric to towrapped-up products. Normal steadiness testing approves rack life claims and capacity proposals for different bundling arrangements, supporting dependable execution in all planning applications.
Important Safety Considerations and Precautions
Usage and Handling Guidelines
While cytisine appears to have fabulous security profiles in clinical ponders, legitimate utilization rules guarantee ideal results. Pregnant and nursing ladies, as well as people with certain cardiovascular conditions, ought to maintain a strategic distance from cytisine-containing products. Proficient meetings are vital sincmedicationte intelligent may occur with solutions influencing the central nervous system. Its impacts on blood pressure and heart rate, moreoverr require checking in delicate populations. Fabricating security measures incorporate appropriate ventilation, defensive gear, and minimizing tidy inward breath, supported by Fabric Security Information Sheets for mechanical handling.
Storage and Quality Assurance
Storage conditions play a basic part in maintaining item quality. Cytisine ought to be kept in fixed holders inside temperature-controlled situations to prevent degradation, whereas nitrogen-filledpackagingamplifieses a difference amplifies rack life and maintains potency throughout dispersion. Quality confirmation through third-party testing guarantees item genuineness and immaculateness. Since fake or tainted materials pose noteworthy dangers, provider confirmation remains fundamental for secure and dependable applications across diverse industries.
Conclusion
Cytisine powder speaks to a profitable characteristic arrangement for smoking cessation and research applications. Its interesting component of activity, fabulous security profile, and demonstrated viability make it an appealing alternative to engineered compounds. Quality contemplations, including virtue levels, capacity conditions, and manufacturing measures, altogether affect item execution and client outcomes.
Jiayuan Bio-Tech's commitment to progressive extraction advances, thorough quality control, and economical generation guarantees cytisine powder that meets the demanding needs of pharmaceutical, nutraceutical, and investigative markets. Our comprehensive back-end services and adaptable manufacturing capabilities position us as the perfect accomplice for your cytisine-based product development needs.
Frequently Asked Questions
Q1: What makes cytisine different from nicotine replacement products?
A: Cytisine is a plant-derived alkaloid that acts as a halfway agonist at nicotinic receptors, giving smoking cessation support without delivering more nicotine into the system. This common approach makes a difference in decreasing desires while minimizing withdrawal side effects through a gentler component than conventional nicotine substitution therapies.
Q2: How should cytisine powder be stored to maintain its potency?
A: Store cytisine powder in fixed holders in cool, dry conditions absent from coordinate light. Keep up temperature underneath 25°C and the relative humidity under 60%. Legitimate capacity with nitrogen-filled bunding can expand rack life past three a long time protecting dynamic compound levels.
Q3: What purity levels are available for different applications?
A: We offer pharmaceutical-grade cytisine powder with ≥99% purity for medical and supplement applications, and cosmetic-grade material with ≥95% purity for personal care products. Research-grade specifications with detailed analytical documentation are available for laboratory and clinical study requirements.
Partner with Jiayuan Bio-Tech for Superior Cytisine Powder Solutions
Your product's success and consumer happiness are affected by your choice of cytisine powder supplier. The pharmaceutical-grade cytisine powder offered by Jiayuan Bio-Tech is of the highest quality, consistently priced, and supplied by a reliable manufacturer. The elimination of market volatility and the guarantee of dependable product availability are both achieved via our vertically integrated supply chain.
All the way through the process of developing your product, our seasoned staff is here to provide you with full technical assistance. We work as a team with you to reach your goals, providing support from the beginning of the formulation process all the way through to scaling up. Larger vendors aren't always able to satisfy the precise needs of smaller projects, but custom specs and small-batch capabilities may.
The automated control systems and state-of-the-art manufacturing facilities provide the uniformity from batch to batch that your quality requirements need. Our purifying procedures are patented, so no one else can make them. As a result, our goods are better. We guarantee sustainable sourcing procedures while maintaining cost benefits due to our location near China's key raw material-producing areas.
Use our premium cytisine powder as a starting point for any kind of study, from making smoking cessation supplements to designing novel formulations. With the same level of care and precision, our versatile manufacturing capability can handle both large-scale commercial projects and specific research applications.
Ready to experience the Jiayuan Bio-Tech difference? Contact us at sales@jayuanbio.com and sales1@jayuanbio.com to discuss your cytisine powder requirements and discover how our expertise can enhance your next project.
References
1. Walker, N., et al. (2014). Cytisine versus nicotine for smoking cessation. New England Journal of Medicine, 371(25), 2353-2362.
2. Ranjan, A., et al. (2015). Cytisine: A promising smoking cessation aid. Journal of Pharmacology and Pharmacotherapeutics, 6(4), 204-209.
3. Tutka, P., & Zatonski, W. (2006). Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. Pharmacological Reports, 58(6), 777-798.
4. Gómez-Coronado, N., et al. (2018). Current and emerging pharmacotherapies for cessation of tobacco smoking. Pharmacotherapy, 38(2), 235-258.
5. Benowitz, N. L., & Burbank, A. D. (2016). Cardiovascular toxicity of nicotine: Implications for electronic cigarette use. Trends in Cardiovascular Medicine, 26(6), 515-523.
6. Cahill, K., et al. (2016). Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database of Systematic Reviews, 5, CD009329.
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