Hydroxocobalamin Powder

High-Purity Hydroxocobalamin Powder - Pharmaceutical Grade Vitamin B12 Solution for Global Health Applications

Xi'an Jiayuan Bio-tech Co., Ltd. offers pharmaceutical-grade Hydroxocobalamin Powder (CAS: 13422-51-0) manufactured under stringent GMP standards with over 20 years of production expertise. Red crystalline powder Red crystalline powder with molecular weight of 1346.355 and consistency of quality from batch to batch via modern quality control methods. We have a registered capital of 30 million RMB and have FSSC2000/ISO2000/HALAL/KOSHER/HACCP certifications. We provide dependable vitamin B12 derivatives with scalable manufacturing capacity from 500g MOQ to bulk orders and provide 24/7 after-sales service and worldwide shipping networks.

What Is Hydroxocobalamin Powder?

This product is a naturally occurring form of Vitamin B12 with a stable molecular framework and outstanding therapeutic effects. This form differs from cyanocobalamin in that it is easily converted to the active coenzyme forms in the body without the need for the metabolic detoxifying processes.

It is a red crystalline powder with the chemical formula C62H89CoN13O15P. It shows good solubility profiles and stability under recommended storage conditions, therefore making it a perfect candidate for pharmaceutical formulation.

Your formulation projects benefit from its longer circulatory residence and higher tissue absorption than standard B12 formulations. This is especially useful in therapeutic applications when bioavailability over a long period of time is required.

 

 

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COA

Product Name	Hydroxocobalamin Powder
Ref standard	According with the enterprise standard
Item	Requirements			Results
Assay	98.5%-100.5%			99.60%
Odor	Characteristic			conforms
Appearance	Dark Red Crystalline Powder			conforms
Taste	Characteristic			conforms
Particle Size	NLT 100% Through 80 mesh			conforms
Loss on Drying	<12.0%			2.20%
Total Heavy Metals	≤10ppm			conforms
Arsenic	≤3ppm			conforms
Lead	≤3ppm			conforms
Total Impurities	≤3.0%			1.70%
Single impurities	≤1.0%			<1.0%
Total Plate Count	≤1000cfu/g			15cfu/g
Total Yeast & Mold	≤100cfu/g			<10cfu/g
E.Coli	Negative			Negative
Salmonella	Negative			Negative
Conclusion	The product conforms to the enterprise standard

Core Functions

Function Category	Mechanism	Application Value
Metabolic Support	Cofactor for methylmalonyl-CoA mutase	Cellular energy production
Hematopoiesis	DNA synthesis facilitation	Red blood cell formation
Neuroprotection	Myelin sheath maintenance	Nerve signal transmission
Detoxification	Cyanide binding capacity	Antidote formulations
Methylation	Homocysteine metabolism	Cardiovascular health support

The powder's ability to bind and neutralize toxic cyanide compounds positions it as a critical component in emergency medical formulations. Its role in folate-dependent reactions supports optimal cellular function across multiple organ systems.

 

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Application Fields

Pharmaceutical Injectable Solutions: This powder may be added to your sterile products for intramuscular or intravenous injection. It is especially useful in the treatment of pernicious anaemia and other conditions involving B12 deficiency when oral absorption is impaired.

Nutraceutical Supplements: Used in high strength nutraceuticals to help fill vegetarian/vegan dietary gaps. The powder is particularly suited to capsules, tablets and sublingual administration methods needing good bioavailability characteristics.

Emergency Medical Kits: Formulations of antidotes of cyanide intoxication are based on special chelation ability of this chemical. It works fast , binding to your emergency pharmaceutical goods to be therapeutically effective .

Veterinary Medicine: Animal health formulations with benefits of its metabolic support qualities. The powder helps overcome B12 deficits in cattle and companion animals in a variety of delivery options.

Fortified Food Products: Functional food makers include it to enrichment programs for certain demographic groups in need of increased B12 consumption and no synthetic substitutes.

 

 

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Quality Control

We have two GMP-compliant manufacturing lines with many stages of quality control. Every batch is analysed by HPLC to determine the purity, assayed by spectrophotometer to validate potency and tested for microbes as per international pharmacopoeia.

Raw materials are subject to rigorous supplier certification. In-process controls are used to monitor crucial parameters such as pH, moisture content and particle size distribution to maintain uniformity.

Testing of the final product comprises testing for heavy metals, residual solvents analysis, and stability studies as per ICH recommendations. Our quality staff is professionally trained, and has sufficient documentation to enable regulatory compliance for worldwide markets.

Third party lab verification makes you more confident in your purchasing selections. With each shipment you will obtain a complete Certificate of Analysis showing conformance to your criteria.

 

 

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Payment & Shipment

Payment Terms: We may accept several payment terms such as TT, DP, PayPal, Visa, MasterCard, LC, DA, Escrow, etc., to meet your financial needs and local conditions.

Shipping Choices: We work with Fedex, DHL, EMS, UPS, TNT, foreign airlines and shipping firms to make sure that we can transport your order all over the world efficiently. You pick the logistical option that best fits your budget and time restrictions.

Customs Support: For customers lacking import experience, we provide customs clearance assistance in Europe and North America. This service ensures your Hydroxocobalamin Powder reaches your facility without regulatory complications or unnecessary delays.

Packaging & Transportation

Standard packaging utilizes 25kg fiber drums with double-layer food-grade polyethylene bags ensuring product integrity during transit. Alternative 1kg foil bag configurations accommodate smaller orders or sampling requirements.

Custom packaging solutions support your specific handling and storage protocols. Temperature-controlled shipping maintains product stability across climate zones. All containers feature clear labeling with batch numbers, manufacturing dates, and storage instructions.

Our warehouse stocking services enable flexible order scheduling aligned with your production cycles. This approach reduces your inventory costs while maintaining supply continuity.

 

 

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After-sales Service

Our 24/7 technical support team addresses formulation questions, regulatory inquiries, and application challenges throughout your product development cycle. You receive prompt responses from experienced professionals understanding both technical and commercial aspects.

Documentation support includes preparing certificates for regulatory submissions, providing stability data for shelf-life determinations, and supplying technical datasheets for your quality departments.

Should any quality concerns arise, our replacement and refund policies ensure your operations face minimal disruption. We maintain comprehensive traceability enabling rapid investigation and resolution.

 

 

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Certificates

• FSSC22000 Food Safety System Certification
• ISO9001 Quality Management System
• HALAL Certification for Muslim markets
• KOSHER Certification for Jewish dietary requirements
• HACCP Hazard Analysis Critical Control Points
• High-tech Enterprise Certification (Shaanxi Province)
• SGS Third-party Verification

 

 

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Exhibitions

Xi'an Jiayuan Bio-tech takes part in international trade fairs such as Vitafoods Europe, SupplySide West and CPHI Worldwide. These platforms provide us with the chance to present innovations and build direct connection with worldwide partners looking for reputable suppliers of ingredients.

 

 

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Why Choose Us?

Manufacturing Excellence: Over 20 years of experience in natural ingredient production combines with advanced extraction technology and integrated factory infrastructure delivering cost efficiency without compromising quality standards.

Scalable Capacity: Our production capabilities accommodate orders from 500g samples to multi-ton contracts. This flexibility supports your business growth from development through commercial production phases.

Regulatory Expertise: Our team navigates complex international requirements ensuring your product shipments comply with destination country regulations, saving you time and reducing compliance risks.

Competitive Pricing: As a direct manufacturer with 30 professional technical personnel, we eliminate intermediary markups. Your procurement budget achieves greater value through factory-direct pricing and consolidated shipping options.

 

 

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FAQ

Q: What is the minimum order quantity for the product?

A: Our MOQ is 500g to 1kg depending on current stock and your needs, for both development samples and commercial orders.

Q: Could you provide samples for testing?

A: Yes, we provide free samples for qualifying B2B clients. We do not offer retail amounts to customers.

Q: What paperwork is included with each shipment?

A: Each purchase comes with a Certificate of Analysis, MSDS, spec sheet and other certification documentation to assist your regulatory and quality assurance requirements.

Q: Do you have Custom Formulation Services?

A: We do ODM/OEM business, including bespoke specs, package forms and private labelling to meet your brand needs.

Q: How do you ensure product stability during international shipping?

A: Our packaging systems and logistics partnerships maintain appropriate environmental conditions. Stability data supports shelf-life claims under specified storage conditions.

Contact Us

Ready to source premium Hydroxocobalamin Powder for your formulations? Contact our sales team at sales@jayuanbio.com and sales1@jayuanbio.com  for quotations, technical specifications, and partnership opportunities today.