L-Dopa Powder

L-Dopa Powder 98% Purity - Pharmaceutical Grade API from GMP Certified Manufacturer

Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with over 20 years of pharmaceutical expertise, offers pharmaceutical-grade L-Dopa Powder with purity specifications ranging from 15% to 98%. Our premium 98% purity specification is extracted from Mucuna macrocarpa seeds utilising state-of-the-art synthetic technology to comply with international pharmacopoeia requirements. We have GMP manufacturing lines with ISO9001, FSSC22000, HALAL, KOSHER certification. We have thorough HPLC testing to ensure the same quality in all batches. We are able to provide scalable supply to worldwide pharmaceutical API distributors, research institutes and healthcare product developers. 30 million RMB registered capital, 30-member technical staff, 24/7 after-sales service, and competitive factory-direct price.

What Is L-Dopa Powder?

The product (CAS NO.: 59-92-7) is a white crystalline powder extracted from Mucuna macrocarpa seeds and is believed to be the metabolic precursor of dopamine. Molecular formula is C9H11NO4. Molecular weight is 197.19 . It is the only one that can penetrate the blood-brain barrier and be converted to dopamine in the brain.

This pharmaceutical-grade chemical is different from regular neurotransmitter supplements since it focuses on the root cause in the treatment of Parkinson’s disease, the lack of dopamine in the substantia nigra. It works by directly replacing the dopamine that is lost in the brain. This in turn relieves bradykinesia, tremors and stiffness.

We provide grades of 15%, 20%, 40% and 98% purity. The 98% grade is in compliance with USP and EP pharmacopoeia criteria for the manufacture of API.

 

COA

Product Name	L-Dopa Powder
Extract Source	Mucuna macrocarpa Wall		Origin of Herb	China
Used Part	Seed		Solvents	Water &E thanol
Ref standard	According with the enterprise standard
Items	Requirements			Results	Method
Assay	Total Phytosterols ≥98.00%			98.34%	HPLC
Appearance	White to off-white powder			Conforms	Organoleptic
Taste	Characteristic			Conforms	Organoleptic
Loss on drying	≤5.0%			3.69%	5g/100℃/2.5hrs
Ash content	≤5.0%			3.72%	2g/525℃/3hrs
Particle size	95% pass 80 mesh			Conforms	80 mesh screen
Lead(Pb)	≤1ppm			Conforms	Atomic Absorption
Cadmium(Cd)	≤1ppm			Conforms	Atomic Absorption
Mercury(Hg)	≤0.1ppm			Conforms	Atomic Absorption
Arsenic (As)	≤1ppm			Conforms	Atomic Absorption
Ethanol	≤5000ppm			1163ppm	GC
Total Plate Count	≤5000cfu/g			Conforms	CP2015
Mold &Yeast	≤100 cfu/g			Conforms	CP2015
E. Coli	Negative			Not Detected	CP2015
Salmonella species	Non-detected			Not Detected	CP2015
Staphylococcus aureus	Non-detected			Not Detected	CP2015
Non-GMO, Non-Irradiation, Allergen Free
Storage Condition:	Preserve in tight containers at controlled room temperature .
Packing	25kg in drum with double plastic bag inside
Conclusion	The product conforms to the enterprise standard

Functions

L-Dopa Powder serves as the cornerstone Active Pharmaceutical Ingredient for Parkinson's disease management. Its dopamine precursor mechanism enables neurotransmitter restoration where blood-brain barrier penetration is critical.

In pharmaceutical use it is converted to dopamine in the basal ganglia and enhances motor performance. This metabolic route has been shown to decrease muscle stiffness and improve movement coordination 30-60 minutes after injection.

Dopamine metabolism and neurodegenerative disease models in neurological studies are being explored using research-grade apps. It is highly bioavailable, making it a must-have for laboratory studies of brain chemistry.

Its purity grade of 98% guarantees reproducible dosage precision for clinical formulations. The lower concentration grades (15%-40%) are suitable for nutritional supplement applications when milder dopaminergic assistance is desired.

Application Fields

Our pharmaceutical-grade product dominates three key sectors:

Pharmaceutical API Manufacturing: Global generic drug producers use our 98% purity grade as the core ingredient in anti-Parkinson medications. China supplies over 60% of worldwide API demand, with our facility contributing to this critical supply chain.

Research Reagents: Universities and biotech labs utilize our product for neuropharmacology studies. Batch documentation ensures traceability required for clinical trial materials.

Nutraceutical Formulations: Health product manufacturers incorporate controlled-potency grades into cognitive support supplements. Your product development teams can leverage our custom concentration services.​​​​​​​

Certificates

Our facility holds:

• FSSC22000 Food Safety System Certification
• ISO9001:2015 Quality Management System
• HALAL Certification (for Middle East markets)
• KOSHER Certification (for North American clients)
• HACCP System Certification
• GMP Production Line Certification

These credentials enable direct export to EU, USA, and Asia-Pacific pharmaceutical markets. Copies accompany each shipment for your customs clearance.

Quality Control

We implement six-stage quality verification protecting your batch consistency:

Stage 1 – Raw Material Inspection: Botanical identification verification using HPTLC fingerprinting to avoid adulteration of species.

Stage 2 - Monitoring Synthesis: Real-time HPLC analysis during manufacturing guarantees ≥99% purity in 98% of requirements.

Stage 3 – Heavy Metal Screening: ICP-MS testing reveals Lead <3.0 ppm, Arsenic <1.0 ppm, USP <231> standards met

Stage 4 - Optical Rotation: Measuring the specific rotation at [α]20/D confirms purity of the L-enantiomer, and no inactive D-isomers.

Stage 5 – Moisture Control: Karl Fischer titration is used to keep moisture levels below 0.5% to avoid deterioration during storage.

Stage 6 - Microbial Testing Total plate count <1000 CFU/g to guarantee pharmaceutical grade hygiene requirements.

Each batch of L-Dopa Powder includes a Certificate of Analysis detailing all parameters.

 

Payment & Shipment

Payment Terms: We accept T/T (primary), L/C, D/P, PayPal, and major credit cards. Flexible terms available for established partners.

Logistics Partners: Cooperating with FedEx, DHL, UPS, EMS, and TNT ensures 7-15 business day delivery globally. Urgent orders ship within 3-5 days from existing stock.

Customs Support: For EU and USA clients without import experience, we provide commercial invoice documentation and HS code classification assistance. Your designated agent handles local clearance.

Shipping Conditions: Refrigerated transport (2–8°C) with moisture-proof packaging. Inert gas protection available upon request for sensitive shipments.

Packaging & Transportation

The normal packaging is pharmaceutical grade aluminium foil packs with twin PE inner liners. The 1kg units are supplied with desiccant packets and outer boxes to protect against light.

Bulk orders (25kg) ship in fibre drums with vacuum sealed liners. Special packaging demands are accepted for private label customers.

Temperature monitoring tags track storage conditions throughout transit. Cold chain logistics prevent thermal degradation during summer shipments.

All packages comply with IATA regulations for air freight and IMDG codes for sea transport.

 

 

After-sales Service

Our 24/7 technical support team resolves formulation questions within 12 hours. You receive:

• Pre-shipment sample testing (free for orders >5kg)
• Reformulation consultation for failed stability tests
• Replacement guarantee for non-conforming batches verified by third-party labs
• Annual supply contracts with price-lock options

Dedicated account managers track your reorder cycles and proactively suggest inventory replenishment.

 

Exhibitions​​​​​​​

Why Choose Us?

20+ Years Pharmaceutical Expertise: Since 2002, we've supplied research institutions and API manufacturers across 40+ countries.

Scalable Production: Two GMP production lines handle orders from 1kg samples to multi-ton contracts without compromising quality.

Cost Savings: Direct price from manufacturers saves your procurement cost by 15-25% than trading firms.

Complete Documentation:  Each shipment comes with COA, SDS, Certificate of Origin and allergies declarations: less work for you to do on compliance.

Flexible MOQ: Minimum order quantity of 1kg for R&D test and small batch manufacturing run.

 

FAQ

Q: How do you ensure batch-to-batch quality consistency? Can you provide a complete COA for each batch?

A：We implement full-chain quality control from raw material to final product, strictly adhering to purity ≥99% (by HPLC) for our 98% grade. Each batch is accompanied by a complete COA covering purity, moisture, specific optical rotation, and residual solvents to ensure consistency.

Q: What is the MOQ and lead time? Can you handle urgent orders?

A：Standard MOQ is 1 kg. Regular orders are delivered within 7–15 business days. For urgent orders, we can expedite shipment to 3–5 business days depending on stock availability.

Q: Are there special shipping requirements? Who manages customs clearance?

A：Ship under refrigerated conditions (2–8°C) with inert gas protection if required; avoid light and moisture. We provide full export documentation; import clearance is handled by your local agent.

Q: What payment terms are accepted?

A：We primarily accept T/T. L/C, D/P, PayPal, MoneyGram, and Western Union are also available upon negotiation.

Q: Do you provide free samples for testing?

A：Yes, free samples are available for qualified buyers. We do not sell retail quantities to individuals—our products serve B2B pharmaceutical and research clients exclusively.

Contact Us

Ready to secure pharmaceutical-grade L-Dopa Powder for your next production run? Contact our sales team at sales@jayuanbio.com and sales1@jayuanbio.com  for COA samples, pricing quotes, and technical datasheets. Start your order today!