Does Panax Notoginseng Help You Breathe?

Understanding Panax Notoginseng

Panax Notoginseng, also known as Sanqi or Tianqi, is a traditional Chinese medicinal herb that has been used for centuries. It is renowned for its numerous health benefits, including its potential to improve respiratory function. This herb belongs to the Panax genus, which includes other well-known species like Panax ginseng and Panax quinquefolius. Panax Notoginseng Extract is particularly valued for its medicinal properties.

The key bioactive compounds in Panax Notoginseng are saponins, also known as ginsenosides. These compounds have been studied extensively for their pharmacological effects. They are believed to contribute to the herb's anti-inflammatory, antioxidant, and immune-modulating properties, all of which can positively impact respiratory health.

panax notoginseng extract

Mechanisms of Action in Respiratory Health

Panax notoginseng, commonly known as "Notoginseng," has been traditionally used in Chinese medicine for its various health benefits. Several mechanisms by which this herb may exert its therapeutic benefits have been revealed in recent research, which has increasingly focused on its potential effects on respiratory health.

The calming properties of panax notoginseng root extract are one of the essential manners by which it upholds respiratory wellbeing. Numerous respiratory circumstances, including asthma, COPD, and intense respiratory trouble disorder (ARDS), are principally described by irritation.Saponins found in Panax notoginseng, particularly notoginsenosides and ginsenosides, have been shown to prevent the production of cytokines that are associated with inflammation.In order to lessen respiratory tract inflammation, these bioactive compounds can downregulate key inflammatory response pathways like NF-B and MAPK.

Another significant mechanism is the antioxidant capacity of Panax notoginseng. Oxidative stress is known to contribute to the pathogenesis of several respiratory diseases.The herb’s constituents can scavenge free radicals and increase the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase. By mitigating oxidative stress, Panax notoginseng helps protect the respiratory epithelium from damage, thus maintaining the integrity and function of the respiratory system.

In addition, the immunomodulatory properties of Panax notoginseng are beneficial to respiratory health.By stimulating the activity of macrophages, T-cells, and natural killer cells, which are essential for protecting the respiratory system from pathogens, it may enhance the immune response.An enhanced immune system can aid in the prevention of respiratory infections and improve lung health as a whole.

In addition, there is evidence that Panax Notoginseng Extract may enhance pulmonary circulation. The herb's saponins are known to increase blood flow in the lungs by reducing blood viscosity and promoting vasodilation.Improved pulmonary circulation ensures better oxygenation and can be particularly beneficial in conditions like pulmonary hypertension.

Furthermore, Panax notoginseng might have a protective effect on the alveolar-capillary barrier. This barrier is essential for efficient gas exchange in the lungs. By preserving the structure and function of this barrier, the herb can help maintain optimal respiratory efficiency and prevent complications arising from increased permeability, such as pulmonary edema.

In conclusion, Panax notoginseng promotes respiratory health through a variety of means, the most important of which are its anti-inflammatory and antioxidant effects, its ability to modulate the immune system, its ability to improve pulmonary circulation, and its ability to preserve the alveolar-capillary barrier.Although additional clinical research is required to fully establish its efficacy and safety in this context, these combined effects make it a promising adjunct in the management of various respiratory conditions.

Clinical Evidence and Research Studies

Numerous studies have investigated the effects of panax notoginseng root extract on respiratory health. For instance, a study published in the "Journal of Ethnopharmacology" examined the anti-inflammatory and antioxidant effects of ginsenosides in an animal model of asthma. The results indicated that ginsenosides significantly reduced airway inflammation and oxidative stress, leading to improved lung function .

Another research study published in "Phytomedicine" explored the impact of Panax Notoginseng on COPD. The study involved a randomized controlled trial where participants with COPD were given Panax Notoginseng supplements. The findings revealed that the supplement group experienced notable improvements in breathing capacity and reduced symptoms compared to the placebo group .

Furthermore, a review article in "Frontiers in Pharmacology" summarized various studies on the immunomodulatory effects of Panax Notoginseng. The review highlighted the herb's ability to enhance immune responses, which can be beneficial in preventing respiratory infections and mitigating their impact on chronic respiratory conditions.

Dosage and Administration

When considering Panax Notoginseng for respiratory health, it is crucial to follow appropriate dosage guidelines. The dosage may vary depending on the form of the herb used (e.g., root powder, extract, or capsule). It is always best to consult a healthcare professional before starting any new supplement regimen, especially for individuals with existing health conditions or those taking other medications.

For general respiratory health support, a typical dosage ranges from 100 to 200 mg of standardized extract per day. This dosage can be adjusted based on individual needs and the severity of respiratory issues. It is also essential to ensure the product is of high quality, sourced from reputable manufacturers, and free from contaminants.

Panax Notoginseng Extract powder

Safety and Precautions

Panax Notoginseng is for the most part thought to be protected when utilized properly. Nonetheless, similar to any enhancement, it can make likely side impacts and connections with different prescriptions. Gastrointestinal discomfort, headaches, and dizziness are all possible side effects. To keep an eye on any side effects, start with a lower dose and gradually increase it.

People with draining issues or those taking anticoagulant drugs ought to practice alert, as Panax Notoginseng might expand the gamble of dying. Before using this herb, pregnant and breastfeeding women should also talk to a doctor.


In conclusion, Panax Notoginseng Extract holds promise as a natural remedy for improving respiratory health. Its anti-inflammatory, antioxidant, and immune-modulating properties make it a valuable addition to the management of respiratory conditions. While clinical evidence supports its benefits, it is essential to use it under the guidance of a healthcare professional to ensure safety and efficacy.

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1.Wang, J., & Xie, W. (2020). Panax notoginseng Saponins Alleviate Airway Inflammation and Remodeling in a Mouse Model of Chronic Asthma. Phytotherapy Research, 34(3), 544-557.

2.Liu, H., Yang, J., Du, F., Gao, X., & Ma, X. (2018). Panax Notoginseng Saponins Improve Pulmonary Function and Reduce Lung Injury in a Rat Model of Acute Lung Injury. Journal of Ethnopharmacology, 214, 179-186.

3.Guo, Q., Zhao, L., & You, Q. (2021). The Role of Panax Notoginseng and Its Components in Inflammatory Diseases: A Review. Biomedicine & Pharmacotherapy, 135, 111172.

4.Zhu, Z., Zhang, H., & Zhao, L. (2020). The Efficacy and Safety of Panax Notoginseng for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Pharmacology, 11, 599.

5.Zhang, X., Wang, X., & Wu, T. (2017). Pharmacological Effects of Panax Notoginseng on Cellular and Molecular Mechanisms in Cardiovascular and Neuroendocrine Systems. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 77, 158-164.

6.Chen, H., Zhou, X., Liu, Y., & Wang, J. (2013). Panax Notoginseng Saponins Attenuate Cognitive Dysfunction Via Regulating Neurotransmitter Levels and Suppressing Neuronal Apoptosis in APP/PS1 Transgenic Mice. Journal of Ethnopharmacology, 148(3), 798-806.