Premium Alpha-Bisabolol Extract – Natural Anti-Inflammatory Active Ingredient with ≥98% Purity for Advanced Cosmetic & Pharmaceutical Applications
Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with RMB 30 million registered capital, delivers pharmaceutical-grade Alpha-Bisabolol extracted from Anthemis tinctoria L. with an exceptional assay of ≥98%. Our product is produced in 2 GMP standard manufacturing lines and backed by ISO, SGS and HALAL certificates. The product is a mucous liquid, colourless to rice-yellow with water soluble qualities. Our team of 30 specialised technical specialists and 80 staff members assure quality consistency for worldwide formulators of cosmetics and pharmaceuticals that need premium natural actives via stringent testing processes.
What Is Alpha-Bisabolol?
It is a naturally occurring monocyclic sesquiterpene alcohol mostly derived from plant sources such German Camomile and Candeia trees. Our component is in the physiologically active (-)-enantiomer configuration for improved performance over manufactured racemic combinations.
This lipophilic molecule has remarkable stability throughout the pH range of 3 to 11. Unlike ester-based formulations that are prone to hydrolysis, the formulation remains structurally intact throughout storage and application.
The molecule is able to do two things because of its chemical structure. It serves as an anti-inflammatory and penetration booster at the same time for transdermal distribution without affecting the skin barrier properties.
COA
| Product Name | Alpha-Bisabolol | ||||
| Lot No | 240501 | Quantity | 400kg | ||
| Manufacture Date | 2024.05.05 | Expiry Date | 2026.05.04 | ||
| Ref standard | According with the enterprise standard | ||||
| Items | Requirements | Results | Method | ||
| Assay | ≥98% | 98.54% | HPLC | ||
| Appearance | Colorless or rice-yellow mucous liquid | Conforms | Organoleptic | ||
| Taste | Characteristic | Conforms | Organoleptic | ||
| Loss on drying | ≤5.0% | 3.92% | 5g/100℃/2.5hrs | ||
| Ash content | ≤5.0% | 2.57% | 2g/525℃/3hrs | ||
| Melting Point | 125°C | Conforms | 80 mesh screen | ||
| Lead(Pb) | ≤1ppm | Conforms | Atomic Absorption | ||
| Cadmium(Cd) | ≤1ppm | Conforms | Atomic Absorption | ||
| Mercury(Hg) | ≤0.1ppm | Conforms | Atomic Absorption | ||
| Arsenic (As) | ≤1ppm | Conforms | Atomic Absorption | ||
| Ethanol | ≤5000ppm | 1118ppm | GC | ||
| Total Plate Count | ≤5000cfu/g | Conforms | CP2015 | ||
| Mold &Yeast | ≤100 cfu/g | Conforms | CP2015 | ||
| E. Coli | Negative | Not Detected | CP2015 | ||
| Salmonella species | Non-detected | Not Detected | CP2015 | ||
| Staphylococcus aureus | Non-detected | Not Detected | CP2015 | ||
| Non-GMO, Non-Irradiation, Allergen Free | |||||
| Storage Condition: | Preserve in tight containers at controlled room temperature . | ||||
| Packing | 25kg in drum with double plastic bag inside | ||||
| Conclusion | The product conforms to the enterprise standard | ||||
Functions
Effect on inflammation
Our substance suppresses the activity of COX-2 enzyme and downregulates NF-κB transcription factors . Clinical investigations show a considerable decrease of pro-inflammatory cytokines like IL-6 and TNF-α. It is thus appropriate for sensitive skin formulations.
Anti-microbial activity
Bacteriostatic action against Gram-positive bacteria such as Staphylococcus epidermidis and Cutibacterium acnes. It also has antifungal activity against Candida albicans and so helps to keep the microbiota balanced in personal care products.
Frustration Reduction
It is used as a tolerance enhancer in harsh formulas comprising retinoids, AHAs or ascorbic acid. It calms nerve endings to reduce the sensory sense of stinging and burning allowing for larger active concentrations.
Application Fields
Dermo-Cosmetic Solutions
Post-procedure skincare products benefit from its erythema-reducing capabilities. Formulations for post-laser therapy, chemical peel recovery, and acne treatment leverage its dual anti-inflammatory and bacteriostatic properties.
Sun Care Innovations
This active is used to high SPF formulas to help offset irritation caused by UV filters. Lipophilic, so remains in touch with the epidermis for a long time even in water resistant preparations, and prevents chronic uv caused irritation.
Personal Care Functional
Aluminum-free deodorants use its selective antibacterial activity to manage odour. In oral hygiene products, it is used to reduce gingival inflammation and has shown efficacy in many product categories.
Certificates
Our production facility maintains multiple international certifications for Alpha-Bisabolol ensuring regulatory compliance. ISO9001 Quality Management System certification validates our process controls. SGS third-party verification confirms consistent product quality. HALAL certification enables market access across diverse geographical regions.
Payment & Shipment
We provide various payment arrangements, including T/T, L/C, and Paypal, to approved customers. We have dependable worldwide delivery in 5-7 business days via our logistical agreements with FedEx, DHL, EMS, UPS and TNT.
We provide customs clearance service for clients that need help with documents for the European and American markets. The door-to-door delivery alternatives reduce the complexity of your logistics.
Packing and Shipping
The standard package is 1kg aluminium foil bags, 5kg drums and 25kg fibre drums with double PE inner bags. Custom package options are available upon request.
Temperature regulated transportation keeps your goods stable. Our warehouse stocking service allows you to purchase a variety of materials at the same time and send them together to save on freight expenses.
After-sales Service
Technical support includes formulation guidance and dosage recommendations. Our team provides compatibility data for complex multi-active systems. Free samples available for qualified formulators conducting initial testing.
We have open lines of contact for troubleshooting and regulatory documentation demands. Certificates of analysis (CoA) are supplied with every shipment according to the batch.
Why Choose Us?
Benefits for the direct manufacturer
Factory direct price means no middle man mark ups. We have the manufacturing capabilities to accommodate trial numbers and commercial volume requirements with consistent quality.
Technical Expertise
Thirty specialized personnel provide formulation consultation based on two decades of natural extract experience. We understand your challenges with actives integration and stability optimization.
Quality Infrastructure
Two GMP production lines equipped with advanced analytical laboratories ensure rigorous quality verification. Every batch undergoes multiple checkpoint testing before release.
FAQ
Q: Is the natural substance more potent than the synthetic counterpart?
A: Natural grade is 100% active (-)-enantiomer, whereas synthetic grade is a racemic combination with only 50% active isomer. You have to double your synthetic dose to have the same efficacy as natural, therefore the initial cost savings are generally lost.
Q: What is the recommended incorporation method?
A: Add to the oil phase or during cool-down below 50°C. Though heat-stable, lower temperatures minimize oxidation risk. Compatible with standard emulsifiers and surfactants.
Q: Does this ingredient cause sensitization?
A: High-purity grades classify as hypo-allergenic. Our low-farnesol specification (<0.2%) minimizes the primary sensitization risk associated with natural extracts.
Q: What is the effective usage rate?
A: General moisturiser needs 0.1-0.2%. Therapeutic uses such as post-procedure care or sunburn treatment work best at 0.5-1.0%. Diminishing returns at >1% concentrations.
Q: Can I use this with retinol and vitamin C?
A: Definitely. It does not chemically interact with these actives but physiologically decreases the related stinging sensations, boosting consumer tolerance to severe treatments.
Contact Us
Ready to enhance your formulations with premium Alpha-Bisabolol? Contact our technical team at sales@jayuanbio.com and sales1@jayuanbio.com for samples, pricing, and customized solutions tailored to your specific application requirements.
