Horse Chestnut Extract Powder

Premium Horse Chestnut Extract Powder – Standardized Aescin Solution for Pharmaceutical & Nutraceutical Applications

Xi'an Jiayuan Bio-tech Co., Ltd. delivers pharmaceutical-grade Horse Chestnut Extract Powder standardized to 20%-98% Aescin content through two GMP-certified production lines. Since 2002, our facility has produced over 500 batches annually with rigorous EP/USP compliance. This fine hygroscopic powder features 95% particle passage through 80 mesh, ensuring optimal flowability and blendability. Our Beta-Aescin enriched formulation provides superior biological activity compared to standard Alpha-Aescin variants. With ISO9001, HALAL, and KOSHER certifications, we maintain <5% ash content and stringent solvent residue controls. Current inventory allows immediate shipment with MOQ starting at 500g for R&D purposes.

What Is Horse Chestnut Extract Powder?

The product is derived from Aesculus hippocastanum seeds, via a high tech extraction and standardisation procedure. The light yellow to brown-yellow powder obtained comprises the concentrated Aescin constituents, mainly Beta-Aescin which has vasoprotective effects.

This plant extract operates by inhibition of elastase and hyaluronidase enzymes. These activities inhibit proteoglycan network disintegration and so protect the integrity of the capillary wall. The standardised powder guaranties uniform dosages for medicinal and nutraceutical uses.

In our extraction procedure, we regulate the isomeric ratios to favour Beta-Aescin for increased water solubility. Such specificity really helps with bioavailability for oral and topical preparations. The unique bitter taste of the powder indicates the actual phytochemical characteristics.

 

COA

Product Name	Horse Chestnut Extract Powder
Ref standard	According with the enterprise standard
Items	Requirements			Results	Method
Assay	≥98%			98.61%	HPLC
Appearance	White crystalline powder			Conforms	Organoleptic
Ethanol	≤5000ppm			1118ppm	GC
Total Plate Count	≤5000cfu/g			Conforms	CP2015
Mold &Yeast	≤100 cfu/g			Conforms	CP2015
E. Coli	Negative			Not Detected	CP2015
Salmonella species	Non-detected			Not Detected	CP2015
Staphylococcus aureus	Non-detected			Not Detected	CP2015
Non-GMO, Non-Irradiation, Allergen Free
Storage Condition:	Preserve in tight containers at controlled room temperature .
Packing	25kg in drum with double plastic bag inside
Conclusion	The product conforms to the enterprise standard

Functions

The active ingredient Aescin acts by a number of mechanisms to alleviate venous hypertension and to cause vasoconstriction. In the presence of oedema, it increases the resistance of capillaries and reduces the permeability of vessels.

Prostaglandin inhibition and free radical scavenging provide anti-inflammatory effects. This dual process enables soft tissue repair and local oedema reduction. Improved microcirculation promotes the elimination of metabolic wastes, especially useful after exercise.

Antioxidant function protects endothelial cells from oxidative damage. In cosmetic applications, the extract has preventive properties against obvious vascular abnormalities. Clinical investigations verify its effectiveness in the treatment of symptoms of chronic venous insufficiency.

Application Areas

Pharmaceutical Venotonics (B2B) : This powder is being incorporated by formulators into tablets and prolonged release capsules for the treatment of Chronic Venous Insufficiency. Therapeutic vasoconstriction effects of accurate Aescin dosage in complicated physiological conditions.

Cosmeceutical Topicals High solubility grades distribute clearly in anti-couperose creams, thick leg gels and eye contour serums. Its anti-inflammatory characteristics help decrease puffiness and the look of spider veins with non-gritty textures.

Supplements for Sports Recovery: Post exercise mixes using this extract regulate soft tissue irritation and removal of lactic acid. Synergistic combos with Vitamin C or Diosmin magnify vascular support results.

 

Certificates

• ISO9001 Quality Management System
• FSSC22000 Food Safety System
• HALAL & KOSHER Certifications
• HACCP Food Safety Management
• SGS Third-Party Verification

Quality Control

Parameter	Specification
Botanical Source	Aesculus Hippocastanum L.
CAS Number	6805-41-0
Active Content	Aescin 20%, 98%
Appearance	White to light yellow powder
Particle Size	95% pass 80 mesh
Loss on Drying	≤5.0%
Ash Content	<5%
Heavy Metals	≤10ppm
Solubility	Soluble in water and ethanol

Our laboratory conducts HPLC and UV spectrophotometry analysis on every batch of Horse Chestnut Extract Powder. Solvent residue testing ensures methanol levels meet EP/USP limits. Microbial testing follows HACCP protocols with documented traceability from raw material sourcing through final packaging.

 

Payment & Shipment

We accept TT, DP, PayPal, LC, and major credit cards for flexible transaction processing. Shipment executes within 3-5 business days post-payment via FedEx, DHL, EMS, UPS, or TNT based on your regional requirements.

For clients lacking import experience, our logistics team provides customs clearance assistance in European and American markets. This service ensures direct delivery to your facility while minimizing regulatory complexities.

Packaging & Transportation

Standard packaging utilizes double-layer polyethylene bags inside fiber drums (25kg net weight). Moisture-barrier aluminum foil options accommodate hygroscopic sensitivity for long-distance shipping.

Transportation follows UN regulations for botanical extracts. Temperature-controlled logistics maintain product stability during transit. Custom packaging solutions support OEM/ODM specifications with branded labeling options.

 

After-sales Service

Our technical team offers 24/7 consultation on formulation integration and dosage optimization. We provide Certificates of Analysis, MSDS documentation, and regulatory support for product registration processes.

Stability testing data assists with shelf-life determination under various storage conditions. Should quality concerns arise, our replacement guarantee activates within 48 hours of claim verification.

Exhibitions

We showcase every year at Vitafoods Europe, SupplySide West and CPHI Worldwide. These platforms demonstrate our latest extraction technologies and allow for direct technical conversations with R&D teams.

Visit our exhibit to get special samples and discuss any bespoke standardisation needs. Our show calendar is updated quarterly on our website for advance meeting preparations.

 

Why Choose Us?

20+ Years of Manufacturing Experience: Since 2002, we have developed extraction techniques that optimise Aescin yields and preserve isomeric integrity. We achieve consistent quality from batch-to-batch via defined process controls.

Scalable Production Capacity: Two GMP lines to support requests from 500g R&D volumes to multi-ton commercial batches. This flexibility is good for startups and the existing companies.

Integrated Quality Systems In house testing avoids delays by a third party. Our QC laboratory tests raw materials, in-process samples and completed items against worldwide pharmacopoeia standards.

Cost-efficient direct procurement: Factory direct price with no distributor markups. Ordering many botanical extracts as part of combined shipments reduces the logistical cost per unit.

 

FAQ

Q: What's the difference between 20% and 98% Aescin grades?

A: The 20% grade suits dietary supplements and cosmetic formulations where broader phytochemical profiles complement Aescin activity. The 98% pharmaceutical grade concentrate is suitable for accurate dosage in clinical applications with restricted therapeutic windows.

Q: How do I keep the powder to avoid the quality deterioration?

A: Store in tightly closed containers at <25°C and <60% relative humidity. Hygroscopic nature requires moisture-barrier packing. Refrigeration makes the shelf life longer, but you want to let the bottle hang out for a while to get it to room temperature before you open it, otherwise you get condensation.

Q: Can you provide Beta-Aescin content specifications?

A: Yes, our standard extracts contain ≥70% Beta-Aescin within total Aescin content. We offer HPLC chromatograms documenting isomeric ratios upon request for formulations requiring specific pharmacological activity.

Q: Do you offer regulatory documentation for EU market entry?

A: Complete Novel Food assessment support, heavy metal reports per EU 2015/1005, and pesticide residue testing following EU pharmacopoeia chapter 2.8.13 accompany bulk orders destined for European markets.

Q: What's your lead time for customized Aescin concentrations?

A: Custom standardization requires 15-20 business days post-deposit, including stability testing. We recommend pilot batches (5-10kg) before scaling to production volumes.

Contact Us

Ready to enhance your formulations with premium Horse Chestnut Extract Powder? Contact our technical sales team at sales@jayuanbio.com and sales1@jayuanbio.com  for COA samples, pricing, and formulation support today.