Vitamin K2 Mk7 Powder

High-Purity Vitamin K2 Mk7 Powder: Professional-Grade Supplement Ingredient with 99% Trans-Isomer and 20+ Years Manufacturing Excellence

Xi'an Jiayuan Bio-tech Co., Ltd. delivers pharmaceutical-grade Vitamin K2 Mk7 Powder with 99% purity, engineered for superior bioavailability in nutraceutical formulations. Our facility was established in 2002 and has RMB30 million registered capital, with two GMP compliant manufacturing lines, certified by ISO9001, FSSC22000, HALAL and KOSHER. Our solution is based on double-microencapsulation technology with a serum half-life of 72 hours that avoids deterioration in alkaline settings. Our 30-member technical team ensures batch consistency through HPLC testing, maintaining >99% all-trans MK-7 isomeric purity for optimal Osteocalcin and MGP carboxylation in your end products.

COA of Vitamin K2 Mk7 Powder

Product Name	Vitamin K2 Mk7 Powder
Molecular	649.1	CAS number	2124-57-4
Ref standard	According with the enterprise standard
Items	Requirements		Results
Appearance	Off white to light yellow powder		Conforms
Identification	Positive by HPLC retention time		Conforms
Solubility	Vitemin K2 MK-7 is soluble in n-hexane and ethanol，slighty soluble in methanol, and insoluble in water		Conforms
Carrier	Beta-cyclodextrin		Conforms
Particle size	NLT 90% pass 80 mesh		Conforms
Loss on drying	≤5.0%		2.90%
Heavy metal	≤10ppm		＜10ppm
Arsenic (As)	≤1.0ppm		＜1 ppm
Menadione	Not detectable by color reaction		Conforms
Assay(on dry basis)	≥1.0%(as C48H84O2)		1.06%
Total Plate Count	≤10000cfu/g		Conforms
Mold &Yeast	≤200 cfu/g		Conforms
E. Coli	Negative		Conforms
Salmonella	Negative		Conforms
Staphylococcus aureus	Negative		Conforms
Conclusion	The product conforms to the enterprise standard

What Is Vitamin K2 Mk7 Powder?

This ingredient represents Menaquinone-7 in crystalline form, featuring a seven-isoprene side chain that distinguishes it from K1 or synthetic MK-4 variants. Your formulations benefit from extended bioactivity—up to three times longer than competing forms.

Core Functions

Our ingredient provides many benefits for your product development:

Bone Density Improvement: Activates Osteocalcin to bind calcium in bone matrix - increasing mineral density by 2-3% per annum in clinical studies.

Cardiovascular Protection: Carboxylates Matrix Gla Protein (MGP) to prevent arterial calcification, lowering vascular stiffness indicators by up to 15%.

Enhanced Bioavailability: The 72-hour half-life allows for less frequent dosing than MK-4 formulations requiring several daily doses.

Application Fields

1. Synergistic Bone Health Formulations

In Ca-D3-K2 complexes, standard powders degrade within months when blended with calcium carbonate. Our beadlet-form product prevents direct chemical reactions, maintaining 95% potency throughout a 24-month shelf life.

2. Cardiovascular Supplements

Our oil-soluble grade is ideal for high-concentration softgels that mix evenly with medium-chain triglycerides. The goal of this application is arterial compliance in the elderly.

3. FUNCTIONAL DRINKS

Our Cold Water Dispersible (CWD) form is well-suited for RTD beverages and fortified dairy products. It resisted pasteurization at 72° C for 15 seconds without sedimentation or crystallization.

Certifications

Our facility maintains:

• FSSC22000 Food Safety System Certification
• ISO9001 Quality Management System
• HALAL & KOSHER certifications for global distribution
• HACCP hazard analysis protocols
• Private Science and Technology Enterprise status (Shaanxi Province, 2013)

Payment & Shipment

Payment ways: T/T,L/C,Paypal,Visa,MasterCard,Escrow

Delivery Partners: FedEx, DHL, EMS, UPS, TNT, international airlines and shipping firms. We send to 90+ countries in 5-15 days.

Customs Support: We prepare the clearance documents for European and American consignees that have no import expertise and send them straight to your warehouse.

Packaging & Transportation

Standard pack: Double layer polyethylene bags in fiber drums (25kg net). Nitrogen flushing prevents oxidation in transport. ODM / OEM needs with customized packaging including smaller units for R&D sample.

Temperature-controlled logistics hold 2-8°C for delicate compositions. All shipments are accompanied with SGS inspection report and phytosanitary certifications when needed.

Quality Control

We implement USP-aligned testing protocols to guarantee performance in your formulations:

• HPLC Isomeric Analysis: Every batch demonstrates >99% trans-MK-7 content with <1% inactive cis-isomers. Certificates of Analysis document retention times matching reference standards.
• Accelerated Stability Testing: 40°C/75% RH chambers validate 90-110% potency retention over six months, predicting two-year shelf life under ambient conditions.
• Contaminant Screening: Heavy metals (Pb, As, Cd, Hg) test below 1 ppm. Microbial panels confirm absence of Salmonella and E. coli. Residual solvents remain under ICH Q3C limits.
• Physical Characterization: Particle size distribution, bulk density, and flowability testing ensure consistent tableting and encapsulation performance.

After-sales Service

Our 24/7 technical support team assists with:

• Formulation compatibility testing
• Stability study design
• Regulatory documentation for health claims
• Troubleshooting batch-to-batch variations

Free samples (10-50g) are available for qualified manufacturers. We provide reformulation guidance if your initial trials encounter challenges with our Vitamin K2 Mk7 Powder.

Exhibitions

We showcase innovations at global trade events, including:

• VitaFoods Europe (Geneva)
• SupplySide West (Las Vegas)
• CPHI Worldwide (Pharma Ingredients)

Visit our booth to discuss customization options and review COA documentation from recent production runs.

Why Choose Us?

Direct Manufacturer Pricing Factory-direct pricing means 15-30% lower ingredient costs than trading businesses.

Flexible MOQ’s – Small batch orders (1-5kg) for R&D stages. Warehouse stocking services enable pooled shipments of numerous ingredients, reducing freight cost.

20 Years of Experience – 80 Employees, 30 R&D Experts, Pharmaceutical-Grade Precision for Every Batch Since 2002.

Scalable Production: Our GMP lines generate 200-500kg monthly batches with lead times of less than 15 days for typical grades.

FAQ

Q: What's the difference between 0.2% and 98% assay grades?

A: The 0.2% grade uses maltodextrin as a carrier for easier blending in complex formulas. The 98% pure crystal suits high-dose softgels requiring minimal excipients.

Q: Will your powder degrade when mixed with calcium carbonate?

A: Standard powder does react in alkaline environments. Specify our microencapsulated beadlet form—it maintains stability in Ca-D3-K2 matrices for 24 months.

Q: Do you offer fermentation-derived or synthetic sources?

A: Both are available. Fermentation-derived (natto-based) appeals to clean-label brands, while synthetic offers lower cost and allergen-free profiles.

Q: What's your lead time for 100kg orders?

A: Standard grades ship within 7-10 days. Customized microencapsulation requires 15-20 days for production and QC testing.

Q: Can I get stability data for my specific formulation?

A: Yes. Submit your formula matrix, and we'll conduct 3-month accelerated studies at no charge for orders above 50kg.

Contact Us

Partner with a certified manufacturer holding 20+ years of natural extract expertise for Vitamin K2 Mk7 Powder. Request your free sample and technical data sheet today at sales@jayuanbio.com and sales1@jayuanbio.com .