Cooling Agent WS-23
Other Name: N,2,3-Trimethyl-2-isopropylbutamide
Assay: ≥99%
CAS: 51115-67-4
Advantages: Refreshing, long-lasting, fresh, without irritating pungency, without bitterness, and with a low dosage.
Applications: candies, tobacco, beverages, toothpaste, skin cleansing and care products, oral care products, etc.
Certification: ISO9001/Kosher/Organic/halal/IFS/BRC/COSMOS
Sample: Available
Delivery terms: FedEx, DHL, EMS, UPS, TNT, all kinds of the airline, international shipping companies.
We do not sell retail quantities to individuals.
High Quality Cooling Agent WS-23 Supplier
The cooling agent WS-23, chemically known as N,2,3-trimethyl-2-isopropylbutyramide, is a synthetic white crystalline powder. It can bring a refreshing and long-lasting cooling sensation, and has no irritating pungency or bitterness. Its cooling taste is unique, without the smell of mint. The cooling intensity is about 1.5-2 times that of menthol, and the duration can last up to 15-30 minutes. Due to these characteristics, it is widely used in various fields such as food, beverages, cosmetics, tobacco products, and pharmaceuticals, and can achieve good results with a relatively low dosage. JIAYUAN from China have a reputation in the pharmaceutical industry. This Active Pharmaceutical Ingredient supplier is regarded as a very reputed Active Pharmaceutical Ingredient manufacturer and we have R&D facilities that are fully equipped with modern pharmaceutical equipment. Maintaining a high level of quality and integrity in their production line is the basis on which this organization works to provide advanced pharmaceutical solutions to the world.
It’s backed by comprehensive certifications such of ISO, as a factory supplier we can ensure of the stability, purity, and effectiveness in every batch. Whether you're in the pharmaceutical, health product, or cosmetics industry, we provide product tailored to meet your needs. For inquiries, please reach out to sales@jayuanbio.com and sales1@jayuanbio.com.
High Purity & Potency: Our product is meticulously processed to ensure a high concentration of active compounds, ensuring maximum benefits for your products.
Quality Certified We are devoted to offering the very best. We have globally recognized certifications like FSSC2000, ISO2000, HALAL, KOSHER, HACCP to ensure the superior quality of our goods.
customisation Options: We provide comprehensive customisation for certain particle sizes, solubility levels and packaging requirements to meet your purpose.

COA
| Product Name | COOLING AGENT WS-23 | ||
| Ref standard | Enterprise standard | ||
| Items | Requirements | Results | |
| Appearance | white crystalline powder | Conforms | |
| Loss on drying | ≤0.5% | 0.1% | |
| 1H-NMR | Correct | Conforms | |
| Assay | ≥99.0% | 99.8% | |
| Melting Point | 60-63℃ | Conforms | |
| Conclusion | The product conforms to the standard | ||
Cooling Agent WS-23 Features
- Long-lasting Cooling: The cooling effect is remarkable and persistent, which can last for 15-30 minutes, bringing users a long-lasting cooling sensation.
- High Temperature Resistance: Under the condition of continuous high temperature of 200℃, it will not affect the cooling intensity of the product, making it convenient for use in high-temperature treatment processes such as baking in the production process.
- Low Dosage: A good cooling effect can be achieved with a relatively low dosage. Generally, adding 30-100mg of it to 1kg of product is sufficient.
- No Unpleasant Odor: The product has no pungent or irritating sensation, and is refreshing, long-lasting, and fresh. When mixed with other flavors, it will not affect their aroma, and can maintain the original flavor and aroma of the product while providing a cooling sensation.
- Unique Cooling Taste: It has no mint smell, and the duration of the cooling sensation is relatively long. Its cooling intensity is about 1.5-2 times that of menthol.
- Mechanism of Action: It stimulates the temperature receptors in the oral cavity and throat, generating a cold sensation, thus achieving the cooling effect. It does not affect the body's thermoregulatory system and is considered a safe cooling agent.
Functions
1. Sensory Cooling Efficacy
- Cooling Taste: It may rapidly create a cooling feeling in the oral cavity, stimulate the cold receptors in the tongue, and deliver a pleasant and cool taste experience. It may effectively reduce the sense of heat in the mouth. For example, when added to foods such as chewing gum, sweets and drinks, customers may feel the coolness while consuming them, which is very noticeable and comforting in hot weather or after eating spicy cuisine.
- Cooling Olfactory Sensation: In specific application settings, it may also deliver a particular cooling olfactory sensation to a certain degree. For instance, when applied to air fresheners or aromatherapy items, the scent released may make people feel like chilly air, thereby generating a pleasant environment.
- Improving Sensory Stimulation The cold sensation of it stimulates consumers'senses, improves the flavor and taste levels of goods, makes items more appealing and distinctive, stimulates consumers' buying urge, and therefore helps products achieve a competitive edge in the market.
2. Physiological Regulation Efficacy
- Relieving Oral Discomfort: The cooling feeling of it in oral care products helps to relieve the pain and discomfort caused by oral inflammation, ulcers, etc. It also may constrict the local blood vessels in the oral cavity by its cold impact, so it reduces the congestion and swelling of the inflammatory site to some degree, and plays an auxiliary function in easing inflammation. In the meanwhile, its cooling effect may promote the production of saliva, keep the oral cavity wet, and avoid such issues as dry mouth, thereby keeping a healthy oral environment.
- Relieving Skin Symptoms: In some topical skin care products, the cooling efficacy of it can relieve symptoms such as skin itching and redness. For example, an anti-itch ointment added with WS-23, when applied to the itchy area caused by mosquito bites or allergies, can numb the nerve endings of the skin through the cooling sensation, temporarily reducing nerve sensitivity, thereby alleviating the itching sensation and bringing a comfortable feeling to the skin.
- Auxiliary in Reducing the Perceived Body Temperature: When using products containing it, the cold receptors on the skin surface are stimulated and send cold signals to the brain, making the human body feel cool. To a certain extent, it can make people subjectively feel a decrease in body temperature, playing a role in relieving heat and increasing comfort in a hot environment.
3. Psychological Regulation Efficacy
- Refreshing and Invigorating: The powerful cold sensation may stimulate the nervous system and assist eliminate tiredness, increase focus and alertness. For example, if you feel sleepy during work or study, eating a mint candy containing WS-23 or drinking a drink containing this chemical will instantly refresh individuals and increase work and study productivity.
- Relaxing and Stress Relief: The cooling sensation may induce a sense of relaxation and pleasure mentally, which is beneficial in relieving tension and stress. When individuals are tense and anxious, contact with items containing it may make people feel that they are in a cool and pleasant atmosphere with its cooling feeling, which is conducive to relaxing the body and mind and alleviating psychological stress.
Application Areas
- Food Industry: It can be used in chewing gum, hard candies, beverages, chocolates, dairy products, jellies, jams, bread, starchy foods, etc., providing a cooling taste for these foods, and it will not bring a strong mint smell like mint-based cooling agents, and can maintain the original flavor of the food.
- Daily Chemical Products: Widely used in toothpaste, mouthwash, lip balm, shaving cream, soap, wet wipes, facial masks and other products. Using it in toothpaste can bring a cooling feeling to the oral cavity; using it in lip balm can make the lips have a cool touch and improve the user experience.
- Medical Field: It can be used in some topical medications, such as ointments for relieving skin itching or pain. Adding it can provide a cooling sensation, helping to reduce the discomfort of patients.
- Tobacco Products: It can add a cooling taste to tobacco products, improve the smoking experience, and make the smoke more mild and cool.

Certificates
Our product is manufactured in compliance with the highest quality standards and is accompanied by the following certifications: FSSC22000/ISO22000/HALAL/KOSHER/HACCP.

Patents
Jayuan has been deeply involved in the raw material medicine and plant extract industries for over 20 years, with Cooling Agent WS-23, a first-class R&D team and advanced equipment. We have obtained multiple patents.

Package
1kg/Aluminum foil bag, 25kg/Drum. Or according to customer requirements.

Shippment
Global direct delivery by sea, land, and air, with a professional logistics team ensuring on-time delivery, covering markets in Europe, America, and Southeast Asia.

Research and Development
Xi'an Jayuan Bio currently has over 80 employees and a professional R&D team of 30 people. Specializing in the research and testing of plant active ingredients, continuously improving and innovating extraction processes, standardized production processes, and a strong quality control management system, effectively ensuring the stability and bioavailability of product quality.

Exhibition Exchange
Jayuan has participated in industry exhibitions such as CPHI, API, PMEC, Vitafoods Asia for several consecutive years, holding in-depth exchanges and collaborations with pharmaceutical companies, research institutions, industry experts and others from all over the world on core products and the latest technological achievements. Xi'an Jayuan Bio hopes to use exposition exchanges to demonstrate its technical strength and product advantages, grow home and international markets, explore additional collaboration prospects, and contribute to the development of the global pharmaceutical industry.

Why Choose Us?
- Uncompromising Quality: At Jiayuan, we adhere to stringent quality control measures throughout the manufacturing process, ensuring the purity, potency, and safety of our product.
- Scientific Expertise: Supported by a group of old pros and state of the art research offices, we influence logical development to convey prevalent items that meet the developing necessities of our clients.
- Commitment to Sustainability: We prioritize sustainability and environmental responsibility, sourcing our raw materials ethically and implementing eco-friendly practices in our operations.
- Customer-Centric Approach: Our commitment to consumer loyalty drives all that we do, from item improvement to post-deals support, guaranteeing a consistent and compensating experience for our esteemed clients.
- Supply Chain Advantage: We have established a stable raw material supply chain and long-term partnerships with plant cultivation bases and suppliers to ensure stable supply of raw materials and controllable quality.

Contact Us
Jiayuan is your trusted partner for premium quality cooling agent WS-23. Backed by extensive expertise, stringent quality standards, and a commitment to excellence, we deliver products that exceed expectations. Experience the difference with Jiayuan – your gateway to harnessing the benefits of nature's bounty. For inquiries and orders, please contact us at sales@jayuanbio.com, sales1@jayuanbio.com.
If you are interested in our products or would like to discuss cooperation matters, please contact us promptly. We will serve you wholeheartedly.

