Madecassoside Powder

Madecassoside Powder 95% HPLC - Pure Grade Botanical Extract for Skin Repair & Inflammation Control

Xi'an Jiayuan Bio-tech Co., Ltd. specializes in manufacturing high-purity Madecassoside Powder extracted from Centella asiatica (Gotu Kola), available in specifications ranging from 10% to 95% HPLC. Since 2002, with more than 20 years of industry expertise, our GMP-certified manufacturing facilities guarantee consistent quality with molecular formula C48H78O20 and molecular weight 975.13. Our standardised powder provides pharmaceutical-grade purity for collagen synthesis and anti-inflammatory pathways, and offers dermato-cosmetic makers solid solutions with batch consistency and predictable therapeutic effects.

What Is Madecassoside Powder?

It is a pharmaceutical-grade pentacyclic triterpenoid saponin extracted from Centella asiatica herba. This standardised active ingredient has a specified chemical framework (C48H78O20, CAS NO. 34540-22-2) and was developed to address problems with crude plant extracts such as colour instability and uneven potency.

The powder solves important formulation issues in contemporary skincare. It offers a non-steroidal option for damaged skin barriers without the negative effects of corticosteroids. It inhibits the inflammation-aging cycle via the NF-κB inflammatory pathways and pro-inflammatory cytokines such as IL-1α and TNF-α.

Our light yellow to white powder is tackling three pain areas in the industry: Lack of standardisation in botanical actives, poor stability in aqueous formulations and the necessity for clinically proven repair agents in post-procedure recovery solutions.

COA

Product Name	Madecassoside Powder
Ref standard	According with the enterprise standard
Items	Requirements		Results
Appearance	Light yellow to white powder		Conforms
Odor	Characteristic		Conforms
Taste	Characteristic		Conforms
Assays	≥98%		98.69%
Loss on drying	≤5.0%		2.03%
Ash	≤5.0%		2.28%
Sulphated ash	<1.0%		0.607%
Heavy metals	≤10ppm		Conforms
Arsenic	≤1ppm		Conforms
Lead	≤2ppm		Conforms
Hg	Absent		Conforms
Assays(HPLC)	Total Triterpenes 10%		10.12%
Total Plate	≤1000CFU/g		Conforms
Yeast & Mould	≤100CFU/g		Conforms
E. Coli	Negative		Conforms
Staphylococcus	Negative		Conforms
Salmonella	Negative		符合规定 Conforms
Conclusion	The product conforms to the enterprise standard

Functions

Function	Mechanism	Application Benefit
Anti-inflammatory	Inhibits IL-1α, TNF-α, PGE2 secretion	Reduces erythema and irritation
Collagen Synthesis	Stimulates Type I & III collagen production	Enhances skin elasticity and firmness
Barrier Repair	Accelerates keratinocyte differentiation	Restores compromised skin barriers
Wound Healing	Regulates fibroblast activity	Shortens post-procedure recovery time
Scar Reduction	Modulates extracellular matrix remodeling	Minimizes hypertrophic scar formation

The powder is a significant ingredient for formulation scientists producing efficacy-driven medicines, since its dual action spans cosmetic soothing and pharmaceutical-grade tissue regeneration.

Application Fields

This bioactive powder may be used by your formulation teams in many product categories:

Dermatological Care: Can be used in post laser recovery serums and in products for the treatment of atopic dermatitis and rosacea due to its anti-inflammatory characteristics without the dependence on steroids.

Anti-Aging Cosmetics Premium face creams and intense repair ampoules harness its collagen-boosting powers to visibly reduce wrinkles and increase skin density.

Scar Management: It’s powers to modulate the extracellular matrix are used in professional level scar gels and stretch mark treatments.

Sensitive Skin Lines: Barrier repair moisturisers and essences for impaired skin without synthetic irritants.

Its water solubility and heat stability make it suitable for incorporation into a wide variety of formulation systems ranging from emulsions to hydrogels.

Certificates

Xi'an Jiayuan Bio-tech holds comprehensive certifications demonstrating our commitment to quality excellence:

• FSSC22000 & ISO22000: Food safety management system certification
• ISO9001: Quality management system (obtained 2012)
• HALAL & KOSHER: Religious dietary compliance
• HACCP: Hazard analysis and critical control points
• High-tech Enterprise of Shaanxi Province (2013)
• Private Science and Technology Enterprise recognition

These credentials validate our Madecassoside Powder manufacturing capabilities for regulated markets worldwide.

Quality Control

Our 2 manufacturing lines under GMP standard assure strict quality control. Each batch passes through multi-stage testing including raw material authentication, in-process monitoring and end product verification.

The testing criteria include HPLC purity, heavy metal screening (Pb, As, Hg, Cd), microbiological analysis and pesticide residue identification. Our lab staff is skilled and employs the latest in chromatographic technology to ensure that specifications are met.

We have full traceability records from botanical source to finished packaging. A methodical strategy guarantees that all shipments fulfil the criteria of international pharmaceutical and cosmetic ingredients.

Payment & Shipment

We provide various payment options such as TT, DP, PayPal, Visa, MasterCard, DA, LC and Escrow to facilitate your financial procedures.

We have a worldwide logistics network with partners such as FedEx, DHL, EMS, UPS, TNT, foreign airlines and shipping firms. We will help you with customs clearance in Europe and the US and transport the items to your plant if you don’t have import expertise.

This door-to-door solution cuts down on logistical complexity and minimises clearance delays to keep your production schedules on the rails.

Packaging & Transportation

The standard packaging is pharmaceutical grade aluminium foil bags with double PE inner liners within fibre drums. Custom packaging is available for OEM/ODM applications.

We stock the warehouse so you may purchase lesser quantities of several goods and save on the shipping expenses associated with repeating orders. Temperature-controlled storage guarantees the stability of ingredients throughout the supply chain.

All shipments arrive with a Certificate of Analysis (CoA), MSDS and all regulatory papers necessary for customs clearance and regulatory compliance in your market.

Exhibition Exchanges

After-sales Service

Our 24/7 technical support team provides formulation guidance, stability testing recommendations, and regulatory documentation assistance. Free samples are available for evaluation before bulk orders.

With more than 20 years of experience as a direct manufacturer, we can customise specs to suit your product needs. We provide ODM / OEM services to assist private label creation, technical consulting throughout the project.

We maintain transparent communication channels to address quality concerns, delivery inquiries, and technical questions promptly.

Why Choose Us?

Manufacturing Excellence: Two decades of botanical extraction experience with integrated factory operations ensure cost efficiency and quality consistency.

Technical Capability We have 30 expert R&D professionals to develop sophisticated extraction methods to maximise the yield and purity.

Scalable Production: The manufacturing may be scaled up to meet demands from trial batches to commercial scale production, without compromising on the standards.

Global Reach: We have the logistical networks and customs clearance skills to support international buying.

Competitive Pricing: We source directly from the factory, cutting out the expense of middlemen and giving you greater value for your ingredient dollar.

We have a registered capital of RMB 30 million and have autonomous import-export rights, showing our financial strength and operational stability.

FAQ

Q: How long does it usually take to fill bulk orders?

A: Standard manufacturing lead time is 7-15 working days after payment confirmation, depends on order quantity and specification need.

Q: Are you providing technical help for formulation development?

A: Yes, our technical team offers formulation guidance, solubility recommendations, and stability testing protocols to optimize your product performance.

Q: What is the minimum order quantity?

A: MOQ is based on the requirements, often 1kg for trial order. Our warehouse stocking program accommodates adjustable volumes.

Q: Do you sell to the end consumer?

A: No, we exclusively do business with B2B clients, for example manufacturers, distributors and research organisations. Not for retail sale in individual amounts for personal use.

Q: How do you guarantee batch-to-batch consistency?

A: We have an ISO-certified quality system which includes rigorous screening of raw materials, standardised extraction procedures and thorough analytical testing to ensure that all batches are to the same specification.

Contact Us

Ready to elevate your formulation with pharmaceutical-grade Madecassoside Powder? Contact our sales team at sales@jayuanbio.com and sales1@jayuanbio.com for quotations, samples, or technical inquiries.