Gypenosides

High-Purity Gypenosides Extract for Metabolic Health & Performance Enhancement Solutions

Xi'an Jiayuan Bio-tech Co., Ltd. delivers pharmaceutical-grade Gypenosides extracted from Gynostemma pentaphyllum leaves, standardized to 98% purity via HPLC. Our product offers cost-effective alternatives to ginsenosides for metabolic control and cardiovascular support with over 20 years of manufacturing experience and ISO9001 certified production facilities. We have two GMP standard manufacturing lines with ton level capacity per month. Consistent quality is guarantyd with a full set of certifications including ISO, HALAL and KOSHER. Our focused R&D team of 30 specialists ensures dependable supply chains with 3-7 day delivery for stock orders; servicing nutraceutical and pharmaceutical sectors around the globe.

What Is Gypenosides?

The products are dammarane-type triterpenoid saponins of Gynostemma pentaphyllum, which are closely related to ginsenosides of Panax ginseng. These bioactive substances have adaptogenic effects without overstimulation.

Molecularly, certain products (III, IV, VIII, XII) correspond with ginsenosides Rb1, Rb3, Rd, and F2. The identical structure allows equivalent therapeutic benefit at a reduced cost. Our extracts are standardised active compounds for regulatory compliance.

The light yellow powder is very soluble in ethanol and water. This flexibility is useful for many sorts of formulations. The high bioavailability and multi-component synergy provide wide pharmacological advantages that cannot be achieved by solo drugs.

COA

Product Name	Gypenosides
Ref standard	According with the enterprise standard
Items	Requirements			Results	Method
Assay	≥98%			98.54%	HPLC
Appearance	Light yellow fine powder			Conforms	Organoleptic
Taste	Characteristic			Conforms	Organoleptic
Protein Content	≥80%			82.21%	HPLC
Ash content	≤5.0%			3.57%	2g/525℃/3hrs
Mercury(Hg)	≤0.1ppm			Conforms	Atomic Absorption
Arsenic (As)	≤1ppm			Conforms	Atomic Absorption
Ethanol	≤5000ppm			1118ppm	GC
Total Plate Count	≤5000cfu/g			Conforms	CP2015
Mold &Yeast	≤100 cfu/g			Conforms	CP2015
E. Coli	Negative			Not Detected	CP2015
Salmonella species	Non-detected			Not Detected	CP2015
Staphylococcus aureus	Non-detected			Not Detected	CP2015
Non-GMO, Non-Irradiation, Allergen Free
Storage Condition:	Preserve in tight containers at controlled room temperature .
Packing	25kg in drum with double plastic bag inside
Conclusion	The product conforms to the enterprise standard

Functions

Metabolic & Cardio-Vascular Support

Regulates glucose metabolism and insulin sensitivity via activation of AMPK, PI3K/Akt and PPARγ pathways. Clinical research have shown lowered cholesterol levels, body weight and belly fat.

Effects of Neuroprotection

Regulates NF-κB, Nrf2, AKT and ERK1/2 signalling pathways. Preclinical investigations suggest therapeutic promise in Alzheimer’s and Parkinson’s disease, depression and stroke-related disorders.

Performance Gains

Functions as an exercise mimic via gut microbiota alteration and TGR5-cAMP-PKA signalling activation. Increases oxidative Type I muscle fibres, hence enhancing endurance capacity in human trials.

Antioxidant and Anti-Inflammatory Properties

It increases the Nrf2 pathway and antioxidant enzymes (SOD, CAT, GSH-Px). Effectively suppresses NLRP3 inflammasome activation and generation of pro-inflammatory cytokines.

Areas of Application

Food Supplements

Capsules, pills, and powders for weight control and metabolic health. Works well in metabolic syndrome formulations with berberine or alpha-lipoic acid

Functional drinks

Water-soluble grades resist acidic pH in RTD teas and energy drinks. Provides caffeine-free energy without the crash of stimulant effects.

Nutrition for Sports

Boosts performance and recovery from exhaustion via AMPK activation. Ideal for protein mixes and pre-workout formulas for endurance athletes.

Applications in Cosmeceuticals

High purity grades of anti-aging serums protect keratinocytes from UV damage. Anti-inflammatory qualities calm inflammation and stimulate microcirculation.

Pharmaceutical Intermediates;

Raw material for lipid-lowering and metabolism problem medicine. Meets pharmaceutical grade standards for therapeutic use.

Certifications

Our facility holds ISO9001, FSSC22000, HALAL, KOSHER, and HACCP certifications. Each batch includes a Certificate of Analysis with third-party testing reports available upon request.

Products meet EP and USP standards for contaminants. SC Food Production License ensures compliance with international food safety regulations.

Quality Control Standards

Parameter	Specification	Test Method
Purity	98%	HPLC
Appearance	Light yellow fine powder	Visual
Particle Size	80-120 mesh	Sieving
Heavy Metals	<10ppm	ICP-MS
Pesticide Residue	<0.1ppm	GC-MS/MS
Solvent Residue	Ethanol <5000ppm	GC
Microbiology	USP <62> compliant	Culture

We employ dual testing using UV and HPLC for marker compounds of Gypenosides like Gypenoside A and XLIX. HPTLC fingerprinting distinguishes genuine Gynostemma pentaphyllum from substitutes, ensuring biological identity across batches.

Payment & Shipment

Payment Terms: T/T, PayPal, Visa, MasterCard, L/C, D/P, D/A, Escrow

Delivery Partners: FedEx, DHL, EMS, UPS, TNT, international airlines, and shipping companies

We offer customs clearance assistance for Europe and the United States, delivering directly to your facility. This reduces logistics complexity for customers without import experience.

Packaging & Transportation

Standard Packaging: 1kg aluminum foil bags (samples), 5kg bags, 25kg fiber drums

Shipping Options:

• Express: 3-5 days for small orders
• Air Freight: 5-7 days for medium volumes
• Sea Freight: 20-35 days for bulk shipments

Custom packaging available for OEM/ODM services. All materials protect against moisture to maintain powder stability during transit.

After-Sales Service

Our 24/7 technical support team provides formulation guidance and application development. Free samples available for evaluation before bulk orders.

We offer flexible warehouse stocking services to reduce your inventory costs. Customers can purchase multiple products in smaller quantities, minimizing repeated logistics expenses.

Exhibitions

We often attend international trade exhibitions such as Vitafoods Europe, SupplySide West and CPHI Worldwide. Visit us at our booth to discover unique formulas and see our whole range of products.

Why Choose Us?

Factory Direct Pricing The factory direct pricing means no middle man which in turn helps you increase your profit margins substantially.

Scalable Production: Monthly tonnage capacity with 3-7 day lead times for stock products to handle urgent demand variations.

20+ Yrs Expertise: Established in 2002, our seasoned staff guaranties technological dependability and continuous supply chain management.

Full Customisation: Offered in different purity grades (40%-98%), particle sizes and monomer profiles. Private label/OEM services

overseas Delivery Made Easy: We collaborate with top carriers and handle customs clearance help to make overseas delivery simple.

FAQ

Q: How do you maintain batch-to-batch consistency?

A: HPLC testing on every batch against important indicators like Gypenoside A ensures constant quality despite raw material fluctuation.

Q: What purity grades are available and how are they tested?

A: Typical requirements are 50, 80, 98% purity. Testing methods: HPLC or UV, with ≥98% grades for research usage.

Q: What is the lead time?

A：Stock items ship within 3-7 days. Customized specifications require longer production cycles. Monthly capacity reaches several tons.

Q: What packaging and shipping methods are available?

A：1kg foil bags for samples, 25kg fiber drums for bulk. Express, air, and sea freight options match your budget and timeline.

Q: Is it heat-stable for beverage applications?

A：Stable up to 120°C for short durations during hot-filling processes. Avoid prolonged boiling to prevent saponin hydrolysis.

Contact Us

Ready to enhance your formulations with premium Gypenosides? Reach our team at sales@jayuanbio.com and sales1@jayuanbio.com  for technical specifications, quotes, and free samples today!