Cnidium Monnieri Extract

Cnidium Monnieri Extract – High-Purity Botanical Ingredient with 98% Osthole Standardization

Xi'an Jiayuan Bio-tech Co., Ltd. delivers premium Cnidium Monnieri Extract sourced from mature seeds, standardized to 10-98% Osthole purity. We have been in business since 2002 and have over 20 years of extraction experience, with two GMP-certified manufacturing lines and ISO9001, HALAL and KOSHER certifications. We provide ton level bulk orders with customisable MOQs and full traceability from cultivation to final product. Each batch fulfils HPLC validated criteria with moisture ≤5%, ash ≤5% and heavy metals < Pb 2ppm/As 1ppm.

We use sophisticated supercritical CO2 and low temperature extraction technology to retain bioactive coumarins, which we provide as a white crystalline powder (98% quality) or water-soluble ratios (10:1, 20:1) for medicines, cosmetics, vitamins and biopesticides.

What Is Cnidium Monnieri Extract?

The product is a standardised botanical derivative from the dried ripe fruit of Cnidium monnieri (L.) Cusson, a plant of the Apiaceae family. Osthole (CAS NO. 484-12-8), a prenylated coumarin with chemical formula C₁₅H₁₆O₃, is the major bioactive marker.

The passage touches on some of the most pressing issues in the sector. Raw herbal powders ( <1% active constituents) have low lipid solubility. Our improved extract increases the concentration of Osthole from 10% (yellowish-green powder) to 98% (snow white crystalline powder), resolving the bioavailability constraints in formulation development.

Crude tinctures are not purified . High purity extraction eliminates waxes and non target chemicals . This minimises risk of adverse reactions in topical treatments and assures constant HPLC-verified potency for pharmaceutical grade formulations.

Specifications

Parameter	Specification
Botanical Source	Cnidium Monnieri
Part Used	Seeds
Extract Ratio	10:1
Appearance	Fine Powder
Color	Light Brown
Odor	Characteristic
Solubility	Soluble in Water
Heavy Metals (ppm)	<10
Microbiology	Conforms to Standards

COA

Product Name	Cnidium Monnieri Extract
Item	Specification		Result	Test Method
Appearance	White Powder		Conforms	Visual
Odor	Unique smell of Cnidium Fruit		Conforms	Organoleptic
Taste	Unique taste of Cnidium Fruit		Conforms	Olfactory
Bulk Density	Slack Density		43.00g/100ml	USP616
	Tight Density		67.00g/100ml	USP616
Particle Size	95%Through 80 Mesh		Conforms	CP2015
Osthole	≥98.0%		98.26%	HPLC
Moisture	≤1.0%		0.2%	CP2015 (80 oC, 4 h)
Ash	≤1.0 %		0.6%	CP2015
Total Heavy Metals	<10 ppm		Conforms	CP2015
Aerobic Bacterial Count	≤1,000 CFU/g		Conforms	GB4789.2
Yeast	≤100 CFU/g		Conforms	GB4789.15
Mold	≤100 CFU/g		Conforms	GB4789.15
Escherichia Coli	<3.0MPN/g		Conforms	GB4789.38
Salmonella	Not Detected		Conforms	GB4789.4
Staphlococcus Aureus	Not Detected		Conforms	GB4789.10
Conclusion	The product conforms to the enterprise standard

Functions

The product provides multi-system therapeutic advantages supported by pharmacological research.

Antimicrobial & antiinflammatory

Osthole has inhibitory impact on Staphylococcus aureus, Pseudomonas aeruginosa and dermatophytes. It has anti-itch, analgesic and anti-inflammatory effects in dermatological applications.

Assistance for Reproductive Health

In Traditional Chinese Medicine, this extract is used to treat renal shortage, impotence, infertility and lumbar discomfort. Modern research validates its significance as a natural PDE inhibitor that enhances nitric oxide release for better circulation.

Antioxidant & Skin Regeneration

It enhances the suppleness of the skin, controls the formation of melanin and protects against oxidative stress. These qualities make it a useful ingredient in anti-aging and sensitive skin care products.

Agriculture, Bio-Control

The aqueous solution of Osthole was ≥70% effective against wheat powdery mildew and rust. It provides organic certified pest control without hazardous residues left behind.

Areas of Application

Cnidium Monnieri Extract is used in several B2B applications with particular formulation needs.

Drugs

In the Chinese Pharmacopoeia it is used for gynaecological issues, eczema, vulvovaginitis and renal diseases. High purity grades permit the formulation of tablets, capsules and injections.

Personal Care & Cosmetics

Widely used in anti-aging serums, sensitive skin creams and whitening cosmetics. It contains antioxidants and melanin regulators to combat premature ageing and hyperpigmentation.

Dietary Supplements

Libido boosters and immunity boosters formulated into men's health goods. Typical doses are 10-50mg per serving and need oil-based delivery methods or cyclodextrin inclusion for maximum absorption.

Biopesticides

It is used as a botanical fungicide for aphids and powdery mildew and the high purity extract is used in organic agricultural operations. It is certified as an organic agricultural input for non-chemical crop protection.

Certificates

• ISO9001 Quality Management System (Certified 2012)
• FSSC22000 Food Safety System Certification
• HALAL & KOSHER Certifications
• HACCP System Compliance
• Shaanxi Province High-tech Enterprise (2013)
• Private Science and Technology Enterprise (Shaanxi Province, 2013)

Quality Control

Parameter	Specification
Active Ingredient	Osthole 10%-98% (HPLC)
Appearance	White crystalline powder (98%); Yellow-green powder (10%-50%)
Moisture	≤5%
Ash Content	≤5%
Heavy Metals	Pb ≤2ppm, As ≤1ppm
Microbial Limits	Total Plate Count ≤1000cfu/g, Yeast & Mold ≤100cfu/g
Shelf Life	24 months (sealed, cool, dark storage)

Every batch includes Certificate of Analysis (COA) with third-party test reports and MSDS documentation. Our professional quality teams monitor from raw material selection through production to final inspection.

Payment & Shipment

Payment Terms

We accept T/T (bank transfer), L/C (letter of credit), PayPal, Visa, MasterCard, Western Union, MoneyGram, and Alibaba Trade Assurance. Flexible options accommodate your regional banking preferences.

Delivery Options

Courier Services: DHL, FedEx, TNT, EMS, UPS for small orders (door-to-door, 1-5 working days)

Air Freight: For mid-volume orders requiring faster transit

Sea Freight: Cost-effective solution for ton-level bulk shipments (3-7 working days after confirmation)

We provide customs clearance assistance in Europe and the United States for customers without import experience of Cnidium Monnieri Extract.

Packaging & Transportation

Standard Packaging

Samples: 1kg/aluminum foil bag with double PE bags

Bulk Orders: 25kg/fiber drum with double PE bags inside

Free Samples: 10-20g available for quality testing (freight collected)

Our packaging protects from light and keeps out moisture during overseas shipping. For long term storage, high purity grades (≥95%) should be kept at 2-8°C.

After-sales Service

24/7 Technical Assistance

Our staff supports formulation problems, stability testing advice and regulatory submission documents. We cover solubility concerns, pH optimisation and advice on the encapsulating technique.

Regulatory Compliance Assistance

We support your market entry with customized COA formats, allergen declarations, and region-specific compliance documentation.

Flexible Reordering

Warehouse stocking services enable smaller repeat orders. You can purchase multiple products with reduced MOQs, lowering logistics costs and customs complexity.

Exhibitions

Xi'an Jiayuan Bio-tech often participates in international trade exhibitions, such as Vitafoods Europe, SupplySide West, CPHI Worldwide, Natural Products Expo etc. Visit our booth to discuss bespoke specs, examine product samples, and explore cooperation prospects.

Why Choose Us?

Over 20 Years of Experience

Since 2002, we have been improving extraction technology and supply chain management. We have a staff of 80 people, 30 of whom are skilled R&D and QC professionals.

Direct to Manufacturer Prices

We buy straight from the factory so you avoid the middleman charge. You get competitive prices, flexible order quantities and integrated shipment of several goods.

Complete Traceability

All of them are recorded from the raw material bases in Hebei, Shanxi and Sichuan via extraction, testing and packing. Third party audits to verify our conformity to ISO9001.

Global Logistics Network

We use leading couriers and freight firms to assure dependable international delivery. We manage the customs paperwork so your imports are worry free.

Customization Services

ODM/OEM support allows private labeling, custom specifications, and blend formulations. We adapt particle size, solubility profiles, and packaging to your requirements.

FAQ

Q: How is quality consistency ensured across batches?

A：Active component (Osthole) specifications typically range from 10% to 98%. We use HPLC for assay testing and maintain strict quality control from raw material sourcing to final packaging. Each batch comes with a verifiable COA covering heavy metals (Pb ≤2ppm, As ≤1ppm) and microbial limits. Shelf life is typically 24 months.

Q: What is the lead time?

A：Sample/small orders ship within 1-5 working days. Commercial bulk orders typically require 3-7 working days after order confirmation, depending on stock availability.

Q: Why does 98% extract turn cloudy in water-based beverages?

A: Osthole is lipophilic. Direct addition of water results in precipitation. Stable aqueous dispersion may be obtained using co-solvents (propylene glycol), cyclodextrin inclusion or liposomal encapsulation technique.

Q: Green and white powder, what's the difference?

A: The colour says purity. The extracts of low purity (10 to 50 percent) include chlorophyll and are yellow-green. The extract is recrystallized to provide a white crystalline powder of high purity (>90%) If 98% grade is green it is certainly contaminated.

Q: How does stability depend on pH?

A: Osthole has a lactone ring which is hydrolyzable in alkaline solutions (pH>9). For adequate efficacy during shelf life, formulations should be in the pH range 5.0-7.5.

Contact Us

Ready to source pharmaceutical-grade Cnidium Monnieri Extract? Contact us at sales@jayuanbio.com and sales1@jayuanbio.com  for COA samples, pricing quotes, and custom formulation consultations.