Semaglutide Powder

High-Purity Semaglutide Powder for Pharmaceutical Applications | GMP-Certified GLP-1 Peptide API with ≥98% Assay

Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with RMB 30 million registered capital, supplies pharmaceutical-grade Semaglutide Powder (CAS No.: 910463-68-2) with a minimum assay of ≥98%. In our manufacturing facility we have two GMP standard production lines and are ISO9001, SGS and HALAL certified to fulfill worldwide quality standards. We have a staff of approx. 80 people, more than 30 technical professionals and we can provide dependable raw material solutions supported by extensive logistical networks in Europe and North America, including customs clearance assistance for customers not experienced in imports.

What Is Semaglutide Powder?

The product is a high purity lyophilized Active Pharmaceutical Ingredient (API) of the glucagon-like peptide-1 (GLP-1) receptor agonist class. This synthetic peptide has 94% sequence identity with human GLP-1 and has a C-18 fatty diacid side chain linked to Lysine-26, resulting in improved albumin binding affinity.

This change increases the plasma half-life to roughly 165 hours, allowing once-weekly dosing regimens. It is supplied as a lyophilized powder which is more stable in worldwide transit than liquid formulations and has reduced risks of hydrolysis and degradation connected to temperature.

It is a white powder that is soluble in water. It is the basic raw material used by manufacturers to create injectable and oral administration systems for the treatment of type 2 diabetes mellitus and chronic weight control therapy.

COA

Functions

The product provides many therapeutic mechanisms:

Glycemic Control: Activates GLP-1 receptors – stimulates glucose dependent insulin production and inhibits glucagon release

Weight Control: Reduces appetite via central nervous system pathways, aiding long-term weight loss strategies

Enzymatic Resistance: Structural changes provide strong resistance to degradation by dipeptidyl peptidase-4 (DPP-4)

Cardiovascular Protection Clinical applications reveal a reduction in cardiovascular risk profiles in metabolic disorder patients

Extended Half-Life: Albumin binding prolongs therapeutic effect allowing for easy dosage regimens

Application Fields

Your product finds strategic applications across:

• Pharmaceutical Manufacturing: Raw material for injectable formulations and emerging oral tablet development
• Compounding Pharmacies: Precise dosage customization for individualized patient treatment protocols
• Clinical Research: Metabolic disorder studies and bioavailability enhancement investigations
• Drug Development: Precursor for novel delivery systems and combination therapy research
• Quality Control: Reference standard material for analytical method validation

Quality Control

Our rigorous quality assurance protocols ensure consistent pharmaceutical-grade standards:

All batches undergo rigorous testing including HPLC purity analysis, peptide content, counter-ion determination and stability profile. Our skilled laboratory teams evaluate findings to worldwide pharmacopeia standards before releasing them.

Certificates

Xi'an Jiayuan Bio-tech holds multiple internationally recognized certifications:

• ISO9001 Quality Management System Certification (obtained 2012)
• SGS Certification
• HALAL Certification
• Private Science and Technology Enterprise of Shaanxi Province (2013)
• High-tech Enterprise of Shaanxi Province (2013)

These awards reflect our dedication to manufacturing excellence and regulatory compliance in international markets.

Payment & Shipment

We provide various payment arrangements to suit your buying requirements. We have formed connections with FedEx, DHL, EMS, UPS, TNT and international freight companies for efficient delivery globally.

For temperature sensitive Semaglutide Powder, we use cold chain logistics using dry ice or gel packs to keep the product intact throughout transportation. Real Time Shipment Tracking with Documentation to Support Regulatory Compliance.

We help our customers with customs clearance in Europe and the USA. Cross border logistics are made easy for customers with no import knowledge.

Packaging & Transportation

Your product arrives in pharmaceutical-grade packaging designed to preserve stability:

• Primary Packaging: Sealed aluminum foil bags with desiccant
• Secondary Packaging: Insulated foam boxes with temperature monitoring
• Shipping Method: Express courier with cold chain maintenance or air freight for bulk orders
• Labeling: Full compliance with international shipping regulations including CAS number, batch code, and storage instructions

Packaging options are customized to order quantities and destination needs for maximum protection across the supply chain.

After-sales Service

Our commitment extends beyond delivery:

• Technical Consultation: Professional guidance on reconstitution protocols and storage best practices
• Sample Provision: Available for quality verification before bulk purchase
• Documentation Support: COA, MSDS, and regulatory filing assistance
• Responsive Communication: Dedicated account management via sales@jayuanbio.com
• Problem Resolution: Swift handling of quality concerns with full traceability

Why Choose Us?

Factory-Direct Pricing: We are a manufacturer-direct supply model, so you can eliminate the middle man and lower your costs.

International Logistics Know-How: Benefit from our partner networks for dependable delivery to over 50 countries, including customs clearance help to simplify your import process.

Flexible Order Quantities: Buy many goods with lesser minimums, making inventory management easier and repeat shipment less necessary.

Professional Technical Team: We have thirty professionals capable of providing expert advise on application development and regulatory compliance.

Proven Track Record: Since 2002, we have been supplying global pharmaceutical manufacturers and compounding pharmacies with consistent quality and dependable supply continuity.

FAQ

Q: Is Semaglutide Peptide Raw Powder stable during transportation?

A: Lyophilized powder form of the peptide is stable at room temperature for short time periods (up to 2 weeks) but it is normal practice to send it on ice packs or dry ice to avoid any thermal degradation and to ensure that it arrives intact.

Q: Your raw powder is with Acetate or TFA counterion?

A: Good quality pharmaceutical grade Semaglutide is either Acetate or ion exchanged to remove Trifluoroacetic acid (TFA). High TFA level is harmful and not acceptable for in vivo use.

Q: How do you handle aggregation issues during reconstitution?

A: Aggregation is a frequent property of GLP-1 peptides. We suggest letting the vial approach room temperature before adding buffer and gently swirling rather than shaking, since mechanical shearing may denature the peptide structure.

Q: What is the difference between 'Peptide Content' and 'Purity'?

A: Purity (e.g., 99%) refers to the ratio of target peptide sequence to impurities via HPLC. Peptide Content refers to net peptide weight minus water and counter-ions. High-quality raw powder typically has 80-90% net peptide content of total powder weight.

Q: Can this powder be directly utilized for oral tablets?

A: Semaglutide Peptide Raw Powder is the active ingredient, but oral bioavailability requires complex formulation with permeation enhancers. Using raw powder alone orally results in near-zero absorption due to gastric enzyme digestion.

Contact Us

Ready to secure your pharmaceutical-grade Semaglutide Powder supply? Contact our technical sales team at sales@jayuanbio.com and sales1@jayuanbio.com  for quotations, COA documentation, or samples.