Lipoic Acid Powder

High-Purity Lipoic Acid Powder | Pharmaceutical-Grade Antioxidant | Stable Formulation Solutions

Xi'an Jiayuan Bio-tech Co., Ltd. medicinal Grade Lipoic Acid Powder, ≥99% HPLC confirmed, USP43, for worldwide dietary supplement and medicinal use. Registered capital: RMB 30 million, established in 2002, 20 years of business expertise. We have GMP-certified lines and strict quality control from raw material purchase to the final inspection of the whole manufacturing process. Our crystalline powder is light yellow with an ideal bulk density (0.35-0.45 g/ml) and sharp melting point of 60.0-62.0°C and solves the stability problems of the current formulas.

What Is Lipoic Acid Powder?

An important cofactor for mitochondria and a universal antioxidant, 1,2-dithiolane-3-pentanoic acid (CAS NO.: 1077-28-7) is a fatty acid derivative that contains sulphur.

Because of its amphiphilia, it is able to neutralise free radicals by penetrating cell membranes and cytoplasm. Its dual solubility allows it to be very adaptable to formulation requirements, in contrast to antioxidants that are water-or lipid-only.

The powdered version addresses important issues with the B2B supply chain. As a result, solid pharmaceutical dosage forms like tablets and capsules may be precisely dosed without the oxidative degradation that is common in liquid solutions.

COA

Product Name	Lipoic Acid Powder
Ref standard	According with the enterprise standard
Items	Requirements			Results	Method
Assay(Dried Basis)	99.0%~101.0%			99.85%	HPLC
Appearance	Yellow crystalline powder			Conforms	Organoleptic
Identification	Positive			Conforms	FTIR/HPLC
Particle size	≥80% through 60 mesh			Conforms	USP<786>
Melting Point	60.0-62.0℃			60.80℃	USP<741>
Specific rotation	-1.0°~+1.0°			+0°	USP<781>
Loss on drying	≤0.2%			0.06%	USP<731>
Residue on ignition	≤0.1%			0.03%	USP<281>
Bulk density	≥0.3g/ml			0.45g/ml	USP<616>
Tapped density	≥0.4g/ml			0.59g/ml	USP<616>
Single Impurity	≤0.1%			0.024%	HPLC
Total Impurities	≤2.0%			0.041%	HPLC
Limit of polymer content	Conforms to standard			Conforms	TLC
Cyclohexane	≤3880ppm			970ppm	GC
Ethyl Acetate	≤5000ppm			80ppm	GC
Toluene	≤890ppm			Conforms	GC
Total Heavy Metals	≤10.0ppm			Conforms	USP<231>
Lead(Pb)	≤1.0ppm			Conforms	USP<730>
Arsenic (As)	≤1.0ppm			Conforms	USP<730>
Cadmium(Cd)	≤0.2ppm			Conforms	USP<730>
Mercury(Hg)	≤0.1ppm			Conforms	USP<730>
Total Plate Count	≤1000cfu/g			Conforms	USP<2021>
Mold &Yeast	≤100 cfu/g			Conforms	USP<2021>
E. Coli	Non-detected			Non-detected	USP<2022>
Salmonella species	Non-detected			Non-detected	USP<2022>
Staphylococcus aureus	Non-detected			Non-detected	USP<2022>
Conclusion	The product conforms to the standard

Functions

Our high purity powder provides a variety of biological advantages for your formulation development:

Mitochondrial Energy Production: A crucial cofactor for pyruvate and alpha-ketoglutarate dehydrogenases, which produce cellular ATP.

Glutathione, Vitamin C, and Vitamin E are restored via the Antioxidant Recycling Network, establishing a full defence against oxidative stress.

Blood Sugar Management: Improves insulin sensitivity and peripheral glucose absorption for metabolic health.

Metal Chelation: Binds mercury and arsenic and aids detoxification in therapeutic nutrition formulations.

Application Fields

Your formulation teams may include our powder into a number of high value sectors:

Metabolic Health Supplements: The main API for formulations of diabetes polyneuropathy and insulin resistance. The powder we use is uniformly sized, so the enteric coating sticks uniformly and avoids stomach discomfort to assure release in the intestine.

Cosmeceuticals: Anti-aging serums and lotions exploit its collagen-preserving properties. Liposomal delivery techniques protect it from UV damage and decrease microscopic wrinkles and pores.

Sports Nutrition Products: Pre-workout stacks and nootropic mixtures take use of its capacity to bolster mitochondrial activity. No clumping with the addition of hygroscopic substances such as Creatine or L-Carnitine due to our 20-40 mesh granulation.

Quality Control

Our all batches are produced under the ISO9001 certified quality management system and fulfil the international pharmaceutical standards:

Two GMP-standard manufacturing lines under constant surveillance. Full testing includes HPLC purity, heavy metal screening (Pb ≤0.5ppm, As ≤1.0ppm) and microbiological testing done by professional laboratory facilities.

Raw material verification through multiple suppliers ensures supply continuity. In-process controls monitor critical parameters like temperature exposure and light protection to prevent polymerization degradation.

Final batch release requires multi-point sampling and third-party verification. Stability testing under accelerated conditions confirms shelf-life performance for your inventory planning.

Payment & Shipment

Payment Terms : TT, DP, PayPal, Visa, MasterCard, DA, LC, Escrow

Delivery Partners: FedEx, DHL, EMS, UPS, TNT and other international airlines and shipping firms for flexible logistical options.

Customs Assistance: We give clearing aid in Europe and North America for importers who are new to importing, with direct delivery to your facilities with little complication.

Packaging & Transportation

Standard packaging: 25kg fibre drum with double food grade polyethylene bags inside to prevent moisture and light exposure.

OEM/ODM Projects Available, Custom Packaging. Small sample in aluminium foil packets.

Temperature regulated transport keeps product under 25°C. Light protective packing prevents polymerisation during transport so you have a stable, free flowing powder suitable for immediate processing.

After-sales Service

Our 24/7 technical support team provides formulation consultation and troubleshooting. Free samples available for qualification testing before bulk orders.

Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) accompany every shipment. Regulatory documentation support for your market registration needs.

Certificates

• FSSC22000
• ISO9001
• HALAL
• KOSHER
• HACCP

All Lipoic Acid Powder certifications available for customer audit upon request.

Exhibitions

We regularly attend international exhibitions including:

• Vitafoods Europe (Geneva)
• SupplySide West (Las Vegas)
• CPHI Worldwide

Visit our booth to discuss your specific application requirements with our technical experts.

 

Why Choose Us?

20+ Years Manufacturing Experience : Since 2002 we have been fine-tuning manufacturing procedures to achieve constant pharmaceutical grade quality.

Scalable Production Capacity: We have many production lines, which allows us to manage requests from 1kg samples up to multi-ton contracts without any compromise in quality.

Cost-Effective Direct Sourcing Factory direct price means no middlemen markups. The flexibility of minimum order numbers helps lower your inventory risk.

Integrated Quality Systems: 30 expert technical people assure each batch fulfils your criteria via extensive testing processes.

FAQ

Q: What's the difference between racemic and R-form Alpha Lipoic Acid?

A: Racemic (DL) contains equal parts R- and S-isomers. Only R-form is biologically active. Our standard product is racemic mixture meeting USP43; R-form available upon request for premium formulations.

Q: How do you keep it from polymerising in storage?

A: Store below 25° C in sealed, light-proof containers. We suggest nitrogen flushing for any long term storage (more than 12 months). Our packaging contains desiccant packets and UV blocking agents.

Q: What's your minimum order quantity?

A: 1kg for initial sampling; 25kg for production orders. Multiple products can be combined in single shipment to optimize logistics costs.

Q: Can you provide water-soluble versions?

A: Yes, we offer cyclodextrin-complexed versions with enhanced water solubility for beverage applications. Contact our technical team for formulation support.

Q: Do you sell to individual consumers?

A: No, we supply exclusively to B2B customers including manufacturers, distributors, and research institutions.

Contact Us

Ready to upgrade your formulation with premium Lipoic Acid Powder? Contact our team at sales@jayuanbio.com and sales1@jayuanbio.com for technical datasheets, samples, and competitive quotations today.