Semen Ziziphi Spinosae Extract

High-Purity Semen Ziziphi Spinosae Extract – Standardized Sleep & Neurological Health Solution with Flexible OEM Services

Xi'an Jiayuan Bio-tech Co., Ltd., established in April 2002 with a registered capital of RMB 30 million, specializes in manufacturing Semen Ziziphi Spinosae Extract under ISO9001-certified quality systems. Our extract features quantifiable specifications including Jujubosides 1%-3% and Jujuboside A+B 0.1%-0.25%, alongside flexible extract ratios (4:1-20:1). With two GMP-standard production lines processing over 1,200 tons annually and a professional team of 30 technical personnel, we deliver standardized botanical ingredients meeting both Chinese Pharmacopoeia (2020 Edition) and international compliance requirements for sleep health formulations.

What Is Semen Ziziphi Spinosae Extract?

The product is a concentrated botanical extract from the seeds of Ziziphus jujuba Mill. var. spinosa by extraction with alcohol, low-temperature vacuum concentration and spray-drying. This brown-red powder solves key formulation issues in the sleep health industry, offering standardized bioactive ingredients, mainly jujubosides and flavonoids, which operate on GABA and 5-HT neurotransmitter pathways.

This medicine-food homologous ingredient provides 60%-80% effectiveness for mild to moderate insomnia by regulating the HPA axis unlike synthetic sedatives which have danger of dependence. It lowers stress-related cortisol and extends slow-wave sleep periods without the morning grogginess.

For manufacturers transitioning to clean-label sleep formulations, our extract solves bioavailability inconsistencies common in raw herb powders. Standardized active content ensures dose predictability across production batches—a critical requirement for GMP-compliant supplement manufacturers.

COA

Product Name	Semen Ziziphi Spinosae Extract
Extract Source	ziziphus jujuba mill. var. spinosa(bunge)hu ex h.f.chou		Origin of Herb	China
Used Part	Seed		Solvents	Water &E thanol
Ref standard	According with the enterprise standard
Items	Requirements			Results	Method
Extract Ratio	10:01			10:01	TLC
Appearance	Brownish red powder			Conforms	Organoleptic
Taste	Characteristic			Conforms	Organoleptic
Loss on drying	≤5.0%			4.13%	5g/100℃/2.5hrs
Ash content	≤5.0%			3.78%	2g/525℃/3hrs
Particle size	95% pass 80 mesh			Conforms	80 mesh screen
Lead(Pb)	≤1ppm			Conforms	Atomic Absorption
Cadmium(Cd)	≤1ppm			Conforms	Atomic Absorption
Mercury(Hg)	≤0.1ppm			Conforms	Atomic Absorption
Arsenic (As)	≤1ppm			Conforms	Atomic Absorption
Ethanol	≤5000ppm			1310ppm	GC
Total Plate Count	≤5000cfu/g			Conforms	CP2015
Mold &Yeast	≤100 cfu/g			Conforms	CP2015
E. Coli	Negative			Not Detected	CP2015
Salmonella species	Non-detected			Not Detected	CP2015
Staphylococcus aureus	Non-detected			Not Detected	CP2015
Non-GMO, Non-Irradiation, Allergen Free
Storage Condition:	Preserve in tight containers at controlled room temperature .
Packing	25kg in drum with double plastic bag inside
Conclusion	The product conforms to the enterprise standard

Functions

Our extract delivers multiple validated mechanisms for neurological health applications:

Sleep Architecture Optimization: Jujuboside A extends non-REM sleep time by modulating GABAergic systems. In clinical observations, users with stress-related insomnia showed a reduction in sleep start latency (by 18-25 min) and a reduction in nocturnal awakenings.

Neuroprotective Action: Flavonoid complexes capture free radicals in brain tissue, protecting it against cognitive impairment generated by oxidative stress. This makes the extract suitable for nootropic compositions for mental clarity and attention.

Anxiolytic Properties: Regulates the hypothalamic-pituitary-adrenal (HPA) axis to lower increased cortisol levels, offering natural stress management without benzodiazepine side effects.

Application Fields

Dietary Supplements: Blended into sleep support products in the form of capsules, pills and soft gels. It is sometimes used with melatonin, L-theanine or magnesium to have synergistic relaxing effects.

Functional Foods & Beverages: Offered as sleep teas, ready to drink beverages, nighttime gummies, and effervescent powders. The extract has a mellow taste profile which works well with chocolate-flavoured goods and herbal mixes.

Pharmaceutical Preparations: Used as an adjunct in traditional Chinese medicine preparations for the treatment of neurasthenia and anxiety disorders. Suitable for oral solid dose forms and liquid extracts.

Innovative Delivery Methods: Sublingual sprays and intranasal forms provide new ways to boost bioavailability by avoiding first-pass metabolism, which is perfect for fast-acting sleep aids.

Quality Control

We maintain rigorous quality standards throughout production:

Parameter	Specification
Jujuboside A Content	≥0.2% (HPLC)
Moisture	≤5.0%
Ash Content	≤5.0%
Particle Size	≥90.0% pass 80 mesh
Heavy Metals (Pb/As/Cd/Hg/Cu)	≤0.9/0.5/1/0.2/20 mg/kg
Microbiological Limits	Compliant with national standards
Pesticide Residues	Meets EU/US pharmacopoeia limits

Each batch of Semen Ziziphi Spinosae Extract undergoes third-party testing with complete traceability from GAP-certified cultivation bases. Our laboratory utilizes HPLC, UV spectrophotometry, and TLC for active component verification.

Certificates

• ISO9001 Quality Management System Certification (since 2012)
• HALAL and KOSHER Certifications (available upon request)
• SC Food Production License
• High-tech Enterprise of Shaanxi Province recognition
• Factory audit access and third-party inspection reports available

For the long-term clientele, we provide various payment arrangements such as T/T, L/C and PayPal. Standard lead time 3-7 days for in-stock goods, expedited sample dispatch within 48 hours.

Global logistics service via agreements with FedEx, DHL, EMS, UPS and TNT. If you have no import expertise, we can help you pass customs in Europe and the United States, which is easier and can be delivered door-to-door.

Packaging & Transportation

Standard Packaging Options:

• Sample size: 1kg aluminum foil bag
• Bulk orders: 5kg carton or 25kg fiber drum
• Custom packaging available for private label requirements

All packages are sealed under nitrogen atmosphere to prevent oxidation. Products are stored in cool, dark conditions and maintain 2-year shelf life under proper storage.

After-sales Service

Our technical support team provides formulation guidance for integrating the extract into your product matrix. We offer stability testing data and assist with regulatory documentation preparation for health food registrations.

Should quality issues arise, we guarantee replacement or refund with comprehensive batch traceability. Ongoing technical consultation is available throughout your product development cycle.

Why Choose Us?

Vertical Integration Advantage: We own GAP-certified farms and extraction facilities that handle over 1,200 tons per year, giving us control over the whole supply chain. This provides constant quality of raw materials and a continuous supply during busy seasons.

Direct Manufacturing: By cutting out the middlemen, we provide factory-direct prices. With MOQ beginning from 1kg, we provide flexibility to test your formulas before placing significant purchases.

Turnkey Solutions Powder Extraction to Final Products (Tablets, Beverages, Soft Gels) One-Stop OEM Customization Multiple specifications (2%-5% jujubosides, different extract ratios) to meet different formulation demands.

Global Compliance Expertise: With 80 employees including 30 technical specialists, we navigate complex regulatory landscapes. Our products meet both Eastern and Western pharmacopoeial standards, reducing your procurement risk.

Q: What product certifications and compliance documents do you provide?

A：We provide SC certification (Food Production License) and supply compliant test reports with each batch. Our manufacture conforms to GB 17405 (GMP for Health Foods) and satisfies norms of Chinese Pharmacopeia (2020 Edition). ISO, HALAL and KOSHER certifications available. Factory audit and third party test documents access available.

Q: How do you ensure batch-to-batch quality stability?

A： We regulate quality via standardized alcohol extraction, low temperature vacuum concentration and spray drying method. Each batch is tested for Jujuboside A (≥0.2%), moisture (≤5.0%), heavy metals and microbiological limits. Active components confirmed by HPLC/UV detection. Our raw materials are consistent coming from our GAP-certified plantations.

Q: What is your manufacturing capacity and supply capacity?

A：Our monthly supply capacity is from 1,000kg to 5,000kg, and we process more than 1,200 tons of raw materials each year. We have several manufacturing lines and we can deliver products stably in the busiest seasons. Samples are available with minimum order quantities from 1kg and flexible scaling for commercial orders.

Q: What are your delivery timelines and shipping options?

A：In-stock products ship within 3-7 days after order confirmation. We offer domestic express and logistics for Chinese customers, with international shipping via major carriers. Packaging includes 1kg aluminum foil bags (samples), 5kg cartons, and 25kg fiber drums (bulk). Custom packaging and expedited shipping are available upon request.

Contact Us

Ready to source premium Semen Ziziphi Spinosae Extract for your formulations? Contact our team at sales@jayuanbio.com and sales1@jayuanbio.com for technical specifications, quotations, and sample requests.