Luteolin Powder

Premium Luteolin Powder 98% HPLC – Natural Flavonoid Extract for Advanced Nutraceutical & Pharmaceutical Solutions

Xi'an Jiayuan Bio-tech Co., Ltd., established in 2002 with over 20 years of expertise, supplies high-purity Luteolin Powder standardized to 98% by HPLC. Obtained from the leaves of Reseda odorata L. Yellow acicular crystals. Molecular formula: C15H10O6. CAS number: 491-70-3. We operate two GMP certified manufacturing lines that are certified to ISO9001, FSSC22000, HALAL and KOSHER and provide expandable capacity with stringent quality control. Our integrated production model provides the cost effectiveness you need, while our 24/7 technical assistance and worldwide logistics partners (FedEx, DHL, UPS) provide dependable supply for pharmaceutical, nutraceutical and cosmetic applications.

What Is Luteolin Powder?

It is a highly pure flavonoid aglycone that is scientifically known as 3’,4’,5,7-tetrahydroxyflavone. This bio-active molecule solves key formulation problems in anti-inflammatory and neuroprotective drugs.

Unlike generic flavonoid mixes, our premium grade powder is the solution to the purity-yield problem. It provides pharmaceutical-grade consistency without the allergic protein carryover often associated with peanut-based sources.

It is a strong PDE4 inhibitor and antioxidant. It controls many cellular pathways at the same time including the NF-κB and MAPK signalling cascades. This multi-target activity has advantages over synthetic alternatives acting on single pathways.

Our product passes the clean-label criteria that are important in today’s supplement production. The 98% cut off is used to forecast the dosage accuracy in completed formulations.

COA of Luteolin Powder

Product Name		Luteolin Powder
Ref standard		According with the enterprise standard
Items		Requirements		Results
Assay		98%		99.18%
Ash		≤1.0%		0.45%
Pesticide residue		Negative		Conforms
Heavy metal		<10ppm		Conforms
Appearance		Yellow powder		Conforms
Odor		Characteristic		Conforms
Particle size		100% All pass 80 mesh		Conforms
Moisture		5.00%		1.96%
Total Plate Count		< 1000cfu/g		Conforms
Mold &Yeast		< 100 cfu/g		Conforms
E. Coli		Non-detected		Conforms
Salmonella		Non-detected		Conforms
Conclusion		The product conforms to the enterprise standard

Core Functions

Function Category	Mechanism	Application Benefit
Anti-inflammatory	Inhibits cytokine storm cascade	Reduces chronic inflammation markers
Neuroprotection	Suppresses microglial activation	Supports cognitive clarity post-recovery
Antioxidant Activity	Superior DPPH/FRAP radical scavenging	Protects cells from oxidative stress
Metabolic Support	Enhances insulin sensitivity pathways	Improves glucose metabolism efficiency
Mast Cell Stabilization	Regulates histamine release	Controls allergic response intensity

The compound has excellent thermal stability (melting point ~330°C), and can withstand the rigours of normal production procedures. This stability translates into reliable production batch performance for your requirements.

Application Areas

Neuro-Cognitive Supplements: Our powder is formulated into nootropic mixes that are designed to cross the blood-brain barrier. Brain fog in post-viral recovery treatments is addressed by the greater cell membrane permeability.

Metabolic Health Products: How B2C supplement firms are using it to enhance insulin sensitivity It has good robustness in complicated physiological settings with different glucose concentrations.

Nutricosmetics & Topicals: Dermatological formulations take use of UV-protective qualities to prevent the destruction of collagen. It is a stabiliser for water-in-oil emulsions in anti-aging skin care.

Functional Foods: Beverage and bar makers looking for natural anti-inflammatories may gain from its clean-label profile. Micronised forms (D90 < 10 micron) improve the dispersibility in solid matrices.

Certificates

• FSSC22000 Food Safety System Certification
• ISO9001 Quality Management System
• HALAL & KOSHER Religious Compliance
• HACCP Hazard Analysis Critical Control Points
• SGS Third-Party Verification

Quality Control

Our quality management system covers everything from raw material verification to completed product release. Purity was tested in each batch by HPLC. Heavy Metal Testing (≤10ppm) and Microbial Testing (USP)

Particle size distribution is adjusted to 80-100 mesh to provide homogeneous mixing. Residual solvent testing to confirm compliance with ICH Q3C requirements We will offer Certificates of Analysis (CoA) and third party testing results on request.

Luteolin Powder is stored in temperature controlled facilities to safeguard its product integrity. Real time stability tests verify our promise of 24-36 month shelf life under optimal circumstances.

Payment & Shipment

Payment Terms: T/T, Paypal, L/C, major credit card (VISA/MasterCard) Flexible arrangements for existing relationships.

Shipping Methods: Global logistics support: FedEx, DHL, EMS, UPS, TNT, air and sea freight. If you are not familiar with imports we can help with the customs clearance for European and American markets and ship straight to you.

Packaging & Transportation

Standard packaging: double-layered polyethylene bags in fibre drums (25kg net weight). UV protecting outer layers prevent photodegradation during transport.

OEM/ODM project custom packaging. Climate zones for temperature-controlled shipping Product stability via temperature zones .Shipment Tracking Provides Visibility from Warehouse to Destination.

After-sales Service

Our 24/7 technical team provides formulation consultation and troubleshooting support. We assist with bioavailability enhancement strategies, including lipid carrier co-formulation recommendations.

Free samples available for qualification testing (non-retail quantities). Batch reservation services help you secure supply during peak seasons. Issue resolution protocols guarantee rapid response within 12 hours.

Exhibitions​​​​​​​

Why Choose Us?

Two Decades of Manufacturing Excellence: Since 2002, we've refined extraction processes to maximize yield without compromising purity. Our RMB 30 million facility investment reflects long-term commitment.

Direct Factory Pricing: Eliminate distributor markups. Our integrated supply chain reduces your procurement costs by 15-25% compared to trading companies.

Flexible Order Quantities: Warehouse stocking enables smaller MOQs for multi-product purchases. Consolidate logistics to reduce repeated shipping expenses.

Regulatory Expertise: Our team navigates international compliance requirements, from EU Novel Food regulations to US FDA GRAS status considerations.

FAQ

Q: What is the primary difference between Luteolin from Peanut Shells versus Sophora Japonica?

A: While the molecule is identical, Sophora-derived sources avoid potential allergen declarations associated with peanuts. Sophora extracts yield lighter color profiles preferred in cosmetic applications.

Q: How can we improve bioavailability in capsule formulations?

A: Crystalline luteolin has poor water solubility. We recommend micronized powder (D90 < 10 microns) or co-formulation with lipid carriers like sunflower lecithin to utilize lymphatic transport.

Q: Is the powder stable in aqueous liquid formulations?

A: Chemically stable and physically insoluble in water. For liquid applications, suspension agents, nano-emulsification or pH modification to alkaline conditions are required (however high pH may decrease antioxidant activity over time).

Q: How does it compare to Quercetin?

​​​​​​​A: Choose luteolin for specific neuro-inflammation and mast cell stabilization. It lacks the 3-position hydroxyl group of quercetin allowing better penetration into the membrane and improved efficacy for PDE4 inhibition.

Q: What are the storage parameters for >98% assay?

A: Store in fibre drums, double-bagged in polyethylene. Shelf life: 24-36 month. Store in a cool, dry place out of direct light. UV radiation breaks down flavonoid structure.

Contact Us

Ready to enhance your formulations with pharmaceutical-grade Luteolin Powder? Contact our team at sales@jayuanbio.com and sales1@jayuanbio.com  for technical specifications, samples, and competitive quotations today.