Genistein Extract

Genistein Extract – Premium Isoflavone Ingredient with 98% HPLC Purity for Nutraceutical and Functional Food Applications

Xi'an Jiayuan Bio-tech Co., Ltd., established in April 2002 with a registered capital of RMB 30 million, delivers pharmaceutical-grade Genistein Extract standardized to 98% purity (HPLC) from Sophora japonica L. seeds. The factory has 2 GMP certified manufacturing lines, ISO9001 and HALAL certifications. And there are 30 specific technical people to assure the stability of bioactive compounds. This pale yellow to off-white fine powder (CAS: 446-72-0, Molecular Formula: C15H10O5) is a solution to key formulation problems for hormone-balancing supplements and functional drinks when synthetic alternatives are hamstrung by regulatory hurdles and customer rejection.

What Is Genistein Extract?

The product is a concentrated phytoestrogen of isoflavone class, isolated from seeds of Sophora japonica, by sophisticated chromatographic purification. Our 98% aglycone version has higher absorption and predictable pharmacokinetics compared to the lesser purity soy isoflavones with mixed glycosides.

Its chemical framework (C15H10O5, MW: 270.24) enables selective oestrogen receptor modulation (SERM), making it a useful instrument for managing menopausal symptoms without the hazards associated with synthetic hormones. Through our strict extraction procedure, we eliminate the antinutrients and allergenic proteins from our formula, but we do not remove the delicate hydroxyl groups of the isoflavone that are responsible for antioxidant activity.

This chemical addresses the clean-label difficulty in women’s health products. You get a clinically studied chemical with GRAS-compliant potential…and without the necessity for contentious hormone replacement therapy.

COA 

产品名称 Product Name	金雀花提取物 Genistein Extract
批号 Batch No	240302	数量 Quantity	300kg
生产日期 Manufacture Date	2024.04.10	有效日期 Expiry Date	2026.04.09
检验依据 Ref standard	企业标准 Enterprise standard
项目 Items	检验标准 Requirements		测定结果 Results
外观 Appearance	浅黄白色粉末 Pale yellow white powder		符合规定 Conforms
含量(HPLC) Assay(HPLC)	≥98.00%		98.21%
气味 Odor	特有气味 Characteristic		符合规定 Conforms
硫酸盐灰分 Sulphated ash	≤5.0%		符合规定 Conforms
水份 Moisture	≤5.0%		符合规定 Conforms
粒径 Particle size	80-100目 80-100 mesh		符合规定 Conforms
重金属 Heavy metal	<10.0ppm		符合规定 Conforms
农药残留 Pesticide residue	未测出 Non-detected		符合规定 Conforms
细菌总数 Total Bacteria	< 10000cfu/g		符合规定 Conforms
霉菌 Mold	< 1000cfu/g		符合规定 Conforms
沙门氏菌 Salmonella	未测出 Non-detected		符合规定 Conforms
大肠杆菌 E. coli	未测出 Non-detected		符合规定 Conforms
结论 Conclusion	本产品经检验符合企业标准 The product conforms to the enterprise standard

Functions

The chemical works on health via numerous biological pathways:

Hormonal Balance Support: Mild phytoestrogen (1/1000th estradiol potency) helps with hot flashes and nocturnal sweats and is safer for the endometrium than synthetic oestrogens

Maintaining bone density : Activates the MAPK pathway to induce osteoblast development and reduce osteoclast activity in postmenopausal women and the risk of osteoporosis.

Heart Health: It enhances endothelial function and helps prevent LDL oxidation by increasing nitric oxide generation, offering a natural alternative to statins for cholesterol management.

Antioxidant defence: cell membranes are protected from free radicals under high-oxidative stress situations such as UV exposure or metabolic syndrome by donation of hydroxyl group.

Areas of Application

Product production puts you ahead in a number of marketplaces:

Food supplements and nutraceuticals: in pill and tablet form for Menopause Relief Complexes, Bone Health Stacks and Anti-Aging. 98% purity for accurate dosing. (25-54mg/day)

Functional food and drinks: Protein bars, meal replacements and fortified drinks for women 40+ It is easily dispersed in emulsions and is colourless.

Beauty-from-within formulations use nutraceuticals to improve skin suppleness and collagen. It inhibits tyrosine kinases and assists in recovery from UV damage.

Sports Nutrition: Used in recovery formulae for its anti-inflammatory and muscle protein synthesis regulating properties, especially for endurance athletes suffering from oxidative stress.

Quality Control

Test Item	Specification	Method
Assay (Genistein)	≥98.0%	HPLC
Appearance	Light yellow to off-white powder	Visual
Particle Size	95% through 80 mesh	USP <786>
Loss on Drying	≤2.0%	USP <731>
Heavy Metals (Pb)	≤2.0 ppm	ICP-MS
Arsenic (As)	≤1.0 ppm	ICP-MS
Total Plate Count	<1,000 CFU/g	USP <2021>
Yeast & Mold	<100 CFU/g	USP <2021>

Our professional quality team conducts triple-batch testing of Genistein Extract at raw material intake, in-process monitoring, and final product release stages. Laboratory facilities include HPLC-UV, UPLC-MS/MS, and ICP-MS instruments ensuring compliance with USP, EP, and CP standards.

Certificates

• ISO9001:2015 Quality Management System
• HALAL Certification (Food-Grade Ingredients)
• SGS Third-Party Testing Reports
• Private Science and Technology Enterprise (Shaanxi Province)
• High-tech Enterprise Certification

Payment & Shipment

Payment Terms: T/T,L/C at sight,Paypal,Western Union.

Delivery Partners FedEx, DHL, EMS, UPS, TNT, foreign airlines and ocean freight

Lead Time : 3-5 working days once the payment is confirmed

Customs Support: We provide door-to-door clearance support for Europe and US markets, easing import processes for clients with no expertise.

Packaging & Transportation

Standard Packaging:

• Inner: Double-layer food-grade PE bags (aluminum foil)
• Outer: Fiber drums (25kg net weight) or cartons (1kg foil bags)

Storage Conditions: Keep in cool, dry place away from light. Shelf life: 24 months under proper conditions.

Transportation: Temperature-controlled logistics for sensitive bioactive compounds, with real-time tracking available.

After-sales Service

• Free samples available (10-20g) for quality evaluation
• Technical documentation support (COA, MSDS, TDS)
• Formulation guidance from our R&D team
• Complaint resolution within 48 hours
• Rework or refund guarantee for quality discrepancies

Exhibitions

We actively participate in international trade shows including:

• Vitafoods Europe (Geneva)
• SupplySide West (Las Vegas)
• Fi Europe (Frankfurt)
• CPHI Worldwide

Visit our booth to discuss your Genistein Extract formulation needs and explore partnership opportunities.

Why Choose Us?

Factory-Direct Prices: Cut out the middleman markup with factory-direct sourcing. Our flexible MOQ policy enables you to buy many extracts in combined shipments, which reduces logistical costs per item.

Regulatory Compliance: With 20 years of export expertise, we guarantee your substances fulfil FDA GRAS standards, EU Novel Food laws, and Health Canada NPN criteria.

Dependable Supply Chain: Strategic storage in Shaanxi Province (the centre of Chinese herbal medicine) ensures a steady supply, even during peak season. We are a team of 80 employees, production continuity you can rely on.

Technical Collaboration Our R&D team of 30 can help you with formulation problems, stability testing technique and bioavailability improvement tactics that are specific to your product positioning.

FAQ

Q: How is your product different from soy isoflavones?

A: Our product is 98% pure aglycone genistein from Sophora japonica with 3-5x better bioavailability than soy glycoside mixes. Predictable dosage without allergic soy proteins.

Q: Is this good for vegan capsules?

A: Oh, totally. The extract is 100% plant based and suitable for HPMC and pullulan capsules. We give full vegan certification documents.

Q: How much menopausal formulas do I need to take?

A: Clinical studies often utilise 25-54mg/day. Check with your regulatory adviser for health claim substantiation that applies to your location.

Q: Do you provide microbiological test reports?

A: Yes. All batches are tested for microbiological contaminants (TPC, Y&M, E.coli, Salmonella) as per the requirements set by USP <2021>. Reports are sent with shipments.

Q: How do I mail modest trial orders?

A: For quantity less than 50kg, we may provide express courier (DHL/FedEx) service, it is door to door delivery in 5-7 business days. Tracking data within 24 hours after despatch.

Contact Us

Ready to elevate your formulations with premium Genistein Extract? Request your free sample and technical specifications today. Reach our team at sales@jayuanbio.com and sales1@jayuanbio.com  for immediate support.