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Caffeic Acid Powder

CAS No.:331-39-5
Assay:≥99%
Molecular Formula:C9H8O4
Molecular Weight:180.15
Our Advantages: Scalable production capacity, strict quality control, cost efficiency from integrated factories, over 20 years of experience, advanced technology, and 24/7 after-sales support.
Certificaions: FSSC2000/ISO2000/HALAL/KOSHER/HACCP
Delivery terms: FedEx, DHL, EMS, UPS, TNT, all kinds of the airline, international shipping companies.
Payment: TT/DP/PAY PAL/VISA/DA/LC/MASTER CARD/ESCROW
Customized Service: Supports ODM/OEM
Free sample is available.
We do not sell retail quantities to individuals.

Product Introduction

Caffeic acid powder is a common phenolic acid compound, typically appearing as a yellow crystalline powder.

It's widely found in various medicinal plants, such as Artemisia scoparia (yinchen), Eucommia ulmoides (duzhong), and Lonicera japonica (jinyinhua). As a phenolic acid compound, it possesses diverse pharmacological activities, including the ability to constrict and strengthen blood vessels, enhance blood coagulation, and provide broad-spectrum antibacterial, antiviral, and anti-venom effects. In clinical practice, it is frequently used to prevent and treat various types of surgical and internal bleeding, showing significant efficacy in managing gynecological hemorrhagic conditions. Caffeic acid functions as an antioxidant both in vitro and in vivo, and it is also widely utilized in the cosmetics industry.

Research—including in vitro studies and animal models—has revealed that caffeic acid possesses a range of potential pharmacological properties. Through oxidative mechanisms, it has been shown to inhibit the proliferation of human HT-1080 fibrosarcoma cells. Caffeic acid also exhibits immunomodulatory and anti-inflammatory activities; notably, it can reduce aflatoxin production by more than 95%—a performance superior to that of many other antioxidants. Studies suggest that caffeic acid can counteract the oxidative stress that would otherwise trigger Aspergillus flavus to produce aflatoxins.

 

COA

 

Application Areas

1. Pharmaceutical & Nutraceutical Applications

In clinical and therapeutic formulations, Caffeic Acid is widely utilized as a targeted hemostatic agent and granulocyte/platelet stimulant.

Core Applications: Commonly formulated into oral tablets, capsules, and therapeutic compounds aimed at managing surgical hemorrhages, internal bleeding disorders, and secondary leukopenia/thrombocytopenia.

Mechanism & Efficacy: Works by constricting and reinforcing capillary microvasculature while enhancing clotting factor reactivity to promote rapid hemostasis and bone marrow recovery.

Processing & Bioavailability: Available in micronized grades ($D_{90} < 10 \ \mu\text{m}$) to overcome low natural aqueous solubility, ensuring accelerated dissolution rates and optimized in vivo bioavailability for oral dosage forms.

2. Personal Care & Dermo-Cosmetic Formulations

Driven by its triple-action profile—antioxidant, tyrosinase inhibition, and antimicrobial activity—Caffeic Acid is an ideal active for premium skincare and scalp-care lines.

Key Functional Benefits:

Advanced Brightening & Depigmentation: Acts as a powerful competitive inhibitor of tyrosinase, effectively blocking melanin synthesis to target hyperpigmentation and age spots.

Photoprotection & Anti-Photoaging: Neutralizes UV-induced Reactive Oxygen Species (ROS) and acts as a synergistic UVA absorber, boosting the SPF efficiency of sunscreens and post-sun repair formulations.

Soothe & Calm (Anti-Inflammatory): Reduces skin erythema and scalp irritation, making it suitable for sensitive skin recovery serums and anti-dermatitis shampoos.

Formulation Tip:

Recommended Usage Level: 0.05% – 0.25% in leave-on emulsions, serums, and creams.

Processing Notice: Pre-dissolve in polyols (e.g., Propanediol or Butylene Glycol) or ethanol phase to ensure uniform dispersion.

3. High-Purity Research & Analytical Grade

For laboratory, diagnostic, and academic applications, we supply ultra-high purity Caffeic Acid to support precision testing and biochemical research.

Reference Standard: Used as a benchmark phenolic acid standard for quantifying total polyphenols in natural extracts and food/beverage matrixes.

Assay Tool for Inflammatory Pathways: Serves as a vital tool compound for studying leukotriene synthesis inhibition, immune response modulation, and ROS scavenging kinetics.

MALDI-MS Matrix Material: Thanks to its high laser absorption capacity at specific wavelengths, HPLC-grade Caffeic Acid is widely utilized as a matrix reagent in MALDI-TOF mass spectrometry for peptide and protein structural analysis.

Certifications

As a leading high-tech enterprise, Xi'an Jiayuan Bio specializes in the research, production, and sales of plant extracts, steroid hormone drugs, and progestational hormone drugs. Our company has attained a range of industry-recognized certifications, including ISO, SGS, HALAL, KOSHER, BRC, ORGANIC, ISO9001, and ISO22000, demonstrating our commitment to quality and regulatory compliance.

 

Quality Control

Our advanced laboratory is equipped to perform comprehensive quality inspections at each stage of production. This rigorous process ensures product consistency, purity, and adherence to international standards, safeguarding the integrity of all our offerings.

 

Research & Development

Our dedicated Research & Development team is focused on innovating extraction methodologies, identifying bioactive compounds, and exploring diverse application potentials. This relentless pursuit of scientific advancement empowers us to provide better solutions grounded in research, customized to meet the dynamic demands of the market.

 

Packaging

We provide flexible packaging options ranging from 1kg, 5kg, and 25kg to bulk shipments, all tailored to customer requirements.

 

Transportation

Our transportation solutions encompass sea, land, and air freight, enabling us to address delivery needs with efficiency and flexibility. We also support international express services such as UPS, FedEx, DHL, and TNT, guaranteeing punctual delivery directly to your specified location.

 

After-sales Service

Our professional support team is dedicated to delivering timely technical assistance, helping with documentation, and offering customized solutions. We strive to ensure a seamless and satisfying customer experience throughout the entire purchase process.

 

Industry Exhibitions

Xi'an Jiayuan Bio actively participates in prominent industry exhibitions such as CPHI, API, PMEC, and Vitafoods Asia. These platforms allow us to present our key products and latest technological innovations to pharmaceutical companies, research institutions, and industry experts worldwide. Through these engagements, we aim to highlight our technological capabilities, expand both domestic and international markets, foster collaborative partnerships, and contribute to advancing the global pharmaceutical industry.

 

Contact Us

If you are interested in our Caffeic Acid Powder or wish to explore potential collaboration opportunities, please reach out to us at sales@jayuanbio.com or sales1@jayuanbio.com. We are committed to providing you with exceptional service and a rewarding partnership experience.

Looking forward to your prompt feedback!

 

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